• 26524059188132119242230827955605PublicAssets/5765
    Mitotic cell awaits chromosome alignment
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    Mitotic cell awaits chromosome alignment

    5765

    During mitosis, spindle microtubules (red) attach to chromosome pairs (blue), directing them to the spindle equator. This midline alignment is critical for equal distribution of chromosomes in the dividing cell. Scientists are interested in how the protein kinase Plk1 (green) regulates this activity in human cells. Image is a volume projection of multiple deconvolved z-planes acquired with a Nikon widefield fluorescence microscope. This image was chosen as a winner of the 2016 NIH-funded research image call. Related to image 5766.

    The research that led to this image was funded by NIGMS.
    Public Note
    Internal NoteImage is from a Flickr album of the NIH Image Gallery: https://www.flickr.com/photos/nihgov/27434780341/in/album-72157666897233564/
    Keywordsmitosis cell division spindle DNA genome
    Source
    Date
    Credit LineRobert Lera and Mark Burkard, University of Wisconsin-Madison
    InvestigatorMark Burkard, University of Wisconsin-Madison
    Record TypePhotograph
    Topic Area(s);#Cells;#Genes;#
    Previous Uses
    StatusActive

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