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  • 7467462379233733732049830828490194PublicAssets/6486This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. The CRISPR system has two components joined together: a finely tuned targeting device (a small strand of RNA programmed to look for a specific DNA sequence) and a strong cutting device (an enzyme called Cas9 that can cut through a double strand of DNA). In this frame (2 of 4), the CRISPR machine locates the target DNA sequence once inserted into a cell.<Br><Br>For an explanation and overview of the CRISPR-Cas9 system, see the <a href=" http://www.ibiology.org/ibiomagazine/jennifer-doudna-genome-engineering-with-crispr-cas9-birth-of-a-breakthrough-technology.html">iBiology video</a>, and find the full <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=7036">CRIPSR illustration here</a>. National Institute of General Medical Sciences.National Institute of General Medical Sciences.Illustration

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    This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. The CRISPR system has two components joined together: a finely tuned targeting device (a small strand of RNA programmed to look for a specific DNA sequence) and a strong cutting device (an enzyme called Cas9 that can cut through a double strand of DNA). In this frame (2 of 4), the CRISPR machine locates the target DNA sequence once inserted into a cell.

    For an explanation and overview of the CRISPR-Cas9 system, see the iBiology video, and find the full CRIPSR illustration here.

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    National Institute of General Medical Sciences.

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    National Institute of General Medical Sciences.

    Record Type

    Illustration

    ID

    6486

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