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    Cholesterol and Huntington's disease
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    Cholesterol and Huntington's disease

    2311

    This web-like structure shows the abnormal accumulation of cholesterol in a mouse brain cell that contains an aberrant protein linked to Huntington's disease, a fatal condition marked by a progressive degeneration of brain nerve cells. While the gene underlying the disease has been identified, little is known about how it leads to such neuronal damage. But the discovery that cholesterol builds up in mouse brain cells expressing the Huntington's protein could offer new clues for understanding the mechanism of the disease in humans.
    Public Note
    Internal Note
    Keywordsmicroscopy
    SourceCynthia McMurray, Mayo Clinic
    Date2007-12-07 00:00:00
    Credit LineCynthia McMurray, Mayo Clinic
    Investigator
    Record TypePhotograph
    Topic Area(s);#Injury and Illness;#
    Previous UsesFeatured in the December 19, 2006, issue of Biomedical Beat.
    StatusActive

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