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  • 1190605248010816594302295032971516835PublicAssets/6983Fat tissue from the abdomen of a genetically mosaic adult fruit fly. Genetic mosaicism means that the fly has cells with different genotypes even though it formed from a single zygote. This specific mosaicism results in accumulation of a critical fly adipokine (blue-green) within the fat tissue cells that have reduced expression a key nutrient sensing gene (in left panel). The dotted line shows the cells lacking the gene that is present and functioning in the rest of the cells. Nuclei are labelled in magenta. This image was captured using a confocal microscope and shows a maximum intensity projection of many slices. <Br><Br>Related to images <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6982">6982</a>, <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6984">6984</a>, and <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6985">6985</a>. Akhila Rajan, Fred Hutchinson Cancer CenterAditi Madan, Akhila Rajan’s lab, Fred Hutchinson Cancer CenterPhotograph

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    CellsChemistry, Biochemistry, and PharmacologyGenesTools and Techniques

    Genetic mosaicism in fruit flies

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    Fat tissue from the abdomen of a genetically mosaic adult fruit fly. Genetic mosaicism means that the fly has cells with different genotypes even though it formed from a single zygote. This specific mosaicism results in accumulation of a critical fly adipokine (blue-green) within the fat tissue cells that have reduced expression a key nutrient sensing gene (in left panel). The dotted line shows the cells lacking the gene that is present and functioning in the rest of the cells. Nuclei are labelled in magenta. This image was captured using a confocal microscope and shows a maximum intensity projection of many slices.

    Related to images 6982, 6984, and 6985.

    Source

    Akhila Rajan, Fred Hutchinson Cancer Center

    Credit Line

    Aditi Madan, Akhila Rajan’s lab, Fred Hutchinson Cancer Center

    Record Type

    Photograph

    ID

    6983

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