Search the NIGMS Image and Video
GenesInjury and IllnessTools and Techniques
A mosquito larva with genes edited by CRISPR. The red-orange glow is a fluorescent protein used to track the edits. This species of mosquito, Culex quinquefasciatus, can transmit West Nile virus, Japanese encephalitis virus, and avian malaria, among other diseases. The researchers who took this image developed a gene-editing toolkit for Culex quinquefasciatus that could ultimately help stop the mosquitoes from spreading pathogens.
The work is described in the Nature Communications paper "Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes" by Feng et al.
Related to image 6770 and video 6771.
Valentino Gantz, University of California, San Diego.
Gantz Lab, University of California, San Diego.
Connect With Us: