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CellsMolecular StructuresTools and Techniques
The 3D single-molecule super-resolution reconstruction of the entire nuclear lamina in a HeLa cell was acquired using the TILT3D platform. TILT3D combines a tilted light sheet with point-spread function (PSF) engineering to provide a flexible imaging platform for 3D single-molecule super-resolution imaging in mammalian cells. See 6573 for 3 seperate views of this structure.
Anna-Karin Gustavsson, Ph.D.
Anna-Karin Gustavsson (Department of Chemistry, Stanford University and Department of Biosciences and Nutrition, Karolinska Institutet), Petar N. Petrov (Department of Chemistry, Stanford University), Maurice Y. Lee (Department of Chemistry and Biophysics Program, Stanford University), Yoav Shechtman (Biomedical Engineering Department, Technion, Israel, Institute of Technology), and W. E. Moerner (Department of Chemistry and Biophysics Program, Stanford University).
Photograph
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