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  • 369937030829396066PublicAssets/3334It has been said that gastrulation is the most important event in a person's life. This part of early embryonic development transforms a simple ball of cells and begins to define cell fate and the body axis. In a study published in <i>Science</i> magazine, NIGMS grantee Bob Goldstein and his research group studied how contractions of actomyosin filaments in <i>C. elegans</i> and <i>Drosophila</i> embryos lead to dramatic rearrangements of cell and embryonic structure. In these images, myosin (green) and plasma membrane (red) are highlighted at four timepoints in gastrulation in the roundworm C. elegans. The blue highlights in the top three frames show how cells are internalized, and the site of closure around the involuting cells is marked with an arrow in the last frame. See related image <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=3297">3297</a>.Bob Goldstein, University of North Carolina, Chapel HillChris Higgins, UNC Chapel Hill, and Liang Gao, Janelia FarmVideo

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    Cells

    Four timepoints in gastrulation

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    It has been said that gastrulation is the most important event in a person's life. This part of early embryonic development transforms a simple ball of cells and begins to define cell fate and the body axis. In a study published in Science magazine, NIGMS grantee Bob Goldstein and his research group studied how contractions of actomyosin filaments in C. elegans and Drosophila embryos lead to dramatic rearrangements of cell and embryonic structure. In these images, myosin (green) and plasma membrane (red) are highlighted at four timepoints in gastrulation in the roundworm C. elegans. The blue highlights in the top three frames show how cells are internalized, and the site of closure around the involuting cells is marked with an arrow in the last frame. See related image 3297.

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    Bob Goldstein, University of North Carolina, Chapel Hill

    Credit Line

    Chris Higgins, UNC Chapel Hill, and Liang Gao, Janelia Farm

    Record Type

    Video

    ID

    3334

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