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  • 692283PublicAssets/3307A study published in March 2012 used cryo-electron microscopy to determine the structure of the DNA replication origin recognition complex (ORC), a semi-circular, protein complex (yellow) that recognizes and binds DNA to start the replication process. The ORC appears to wrap around and bend approximately 70 base pairs of double stranded DNA (red and blue). Also shown is the protein Cdc6 (green), which is also involved in the initiation of DNA replication. The video shows the structure from different angles. See related image <a href="/Pages/DetailPage.aspx?imageID2=3597">3597</a>.Huilin Li, Brookhaven National LaboratoryHuilin Li, Brookhaven National Laboratory, and Bruce Stillman, Cold Spring Harbor LaboratoryVideo

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    Molecular Structures

    DNA replication origin recognition complex (ORC)

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    A study published in March 2012 used cryo-electron microscopy to determine the structure of the DNA replication origin recognition complex (ORC), a semi-circular, protein complex (yellow) that recognizes and binds DNA to start the replication process. The ORC appears to wrap around and bend approximately 70 base pairs of double stranded DNA (red and blue). Also shown is the protein Cdc6 (green), which is also involved in the initiation of DNA replication. The video shows the structure from different angles. See related image 3597.

    Source

    Huilin Li, Brookhaven National Laboratory

    Credit Line

    Huilin Li, Brookhaven National Laboratory, and Bruce Stillman, Cold Spring Harbor Laboratory

    Record Type

    Video

    ID

    3307

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