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  • 8366951743534183484337820116713079PublicAssets/2741Like a strand of white pearls, DNA wraps around an assembly of special proteins called histones (colored) to form the nucleosome, a structure responsible for regulating genes and condensing DNA strands to fit into the cell's nucleus. Researchers once thought that nucleosomes regulated gene activity through their histone tails (dotted lines), but a 2010 study revealed that the structures' core also plays a role. The finding sheds light on how gene expression is regulated and how abnormal gene regulation can lead to cancer. Karolin Luger, Colorado State UniversityKarolin Luger, Colorado State UniversityIllustration

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    CellsGenesMolecular Structures

    Nucleosome

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    Like a strand of white pearls, DNA wraps around an assembly of special proteins called histones (colored) to form the nucleosome, a structure responsible for regulating genes and condensing DNA strands to fit into the cell's nucleus. Researchers once thought that nucleosomes regulated gene activity through their histone tails (dotted lines), but a 2010 study revealed that the structures' core also plays a role. The finding sheds light on how gene expression is regulated and how abnormal gene regulation can lead to cancer.

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    Karolin Luger, Colorado State University

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    Karolin Luger, Colorado State University

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    Illustration

    ID

    2741

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