• 92382938630461414149292221995858PublicAssets/2791
    Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 02
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    Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 02

    2791

    Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. It was synthesized by NIGMS grantees E.J. Corey and later by Samuel Danishefsky. Multiple versions of this structure are available as entries 2790-2797.
    Public Note
    Internal Noteobtained by AZM from Timothy Jamison in January 2011 for a Web banner
    Keywordsdrug design, treatment, trabectedin, antitumor, chemotherapy drug, chemo, sarcoma, soft-tissue sarcoma
    SourceTimothy Jamison, Massachusetts Institute of Technology
    Date2011-01-19 00:00:00
    Credit LineTimothy Jamison, Massachusetts Institute of Technology
    Investigator
    Record TypeIllustration
    Topic Area(s);#Chemistry, Biochemistry, and Pharmacology;#Injury and Illness;#
    Previous Uses
    StatusActive

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