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    Sleep and the fly brain
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    Sleep and the fly brain


    In the top snapshots, the brain of a sleep-deprived fruit fly glows orange, marking high concentrations of a synaptic protein called Bruchpilot (BRP) involved in communication between neurons. The color particularly lights up brain areas associated with learning. By contrast, the bottom images from a well-rested fly show lower levels of the protein. These pictures illustrate the results of an April 2009 study showing that sleep reduces the protein's levels, suggesting that such "downscaling" resets the brain to normal levels of synaptic activity and makes it ready to learn after a restful night.
    Public Note
    Internal Notehttp://publications.nigms.nih.gov/biobeat/09-05-20/index.html#1
    SourceChiara Cirelli, University of Wisconsin-Madison
    Date2009-05-21 00:00:00
    Credit LineChiara Cirelli, University of Wisconsin-Madison
    InvestigatorChiara Cirelli, University of Wisconsin-Madison
    Record TypePhotograph
    Topic Area(s);#Molecular Structures;#
    Previous UsesBB 4/09 cool image

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Low9 KB 6/3/2016 3:13 PMaamishral2 (NIH/NIGMS) [C]
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