• 5004125539025020620466308254104272PublicAssets/2331
    Statistical cartography
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    Statistical cartography

    2331

    Like a world of its own, this sphere represents all the known chemical reactions in the E. coli bacterium. The colorful circles on the surface symbolize sets of densely interconnected reactions. The lines between the circles show additional connecting reactions. The shapes inside the circles are landmark molecules, like capital cities on a map, that either act as hubs for many groups of reactions, are highly conserved among species, or both. Molecules that connect far-flung reactions on the sphere are much more conserved during evolution than molecules that connect reactions within a single circle. This statistical cartography could reveal insights about other complex systems, such as protein interactions and gene regulation networks.
    Public Note
    Internal Note
    Keywordsmapping
    SourceLuis A. Nunes Amaral, Northwestern University
    Date2007-12-07 00:00:00
    Credit LineLuis A. Nunes Amaral, Northwestern University
    Investigator
    Record TypeIllustration
    Topic Area(s);#Tools and Techniques;#
    Previous UsesFeatured in the August 16, 2005, issue of Biomedical Beat.
    StatusActive

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Low102 KB 3/29/2019 1:48 PMConstantinides, Stephen (NIH/NIGMS) [C]
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