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    An axolotl—a type of salamander—that has been genetically modified so that its developing nervous system glows purple and its Schwann cell nuclei appear light blue. Schwann cells insulate and provide nutrients to peripheral nerve cells. Researchers often study axolotls for their extensive regenerative abilities. They can regrow tails, limbs, spinal cords, brains, and more. The researcher who took this image focuses on the role of the peripheral nervous system during limb regeneration.

    This image was captured using a stereo microscope.

    Related to images 6927 and 6928.
    Public NoteA salamander that’s glowing purple and has three feathery projections on each side of its head. Light blue spots appear in the salamander’s eyes and throughout its body.
    Internal NoteOn Jan 11, 2023, at 2:59 PM, Prayag Murawala pmurawala@mdibl.org wrote:

    Dear Abbey,

    Feel free to rename images as you may see fit. Image credits: Dr. Marko Pende, MDIBL-LMF and Murawala Lab Let me know, if you need any further details.



    — Prayag Murawala, PhD Assistant Professor Pronouns: he / him / his 159, Old Bar Harbor Road | Bar Harbor, ME 04609, USA 207-288-9880, Ext. 468 | mdibl.org https://murawalalab.mdibl.org & die Klinik für Nieren- und Hochdruckerkrankungen (Clinic for Kidney and Hypertension Diseases) der Medizinische Hochschule Hannover (Hannover Medical School), Carl-Neuberg-Straße 1 | 30625 Hannover, Germany

    https://orcid.org/0000-0002-0607-1059 https://www.ncbi.nlm.nih.gov/pubmed/ Twitter: pmurawala

    Grant information: Sub-project ID 8474 of parent grant 5P20GM104318, PO Yang Zhou; MDI Biological Laboratory Light Microscopy Facility is supported by the Maine INBRE grant GM103423, PO Krishan Arora
    Keywordsresearch organisms, salamanders, amphibians
    SourcePrayag Murawala, MDI Biological Laboratory and Hannover Medical School.
    Credit LineMarko Pende, MDI Biological Laboratory; MDI Biological Laboratory Light Microscopy Facility; and the Murawala Lab, MDI Biological Laboratory and Hannover Medical School.
    InvestigatorLive imaging of a transgenic axolotl (B3Tub:Cherry) showing the developing nervous system (magenta) and Schwann cells (cyan). Recorded on: Stereoskop Zeiss Axio Zoom [Sourcing for additional details in the description is included in IVG metadata form that's on file]
    Record TypePhotograph
    Topic Area(s);#Tools and Techniques;#
    Previous Uses

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Purple Axolotl_M.jpg
Medium92 KB 3/28/2023 2:13 PMBigler, Abbey (NIH/NIGMS) [C]
Purple Axolotl_S.jpg
Low22 KB 3/28/2023 2:13 PMBigler, Abbey (NIH/NIGMS) [C]
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