• 223610647156536111853215965955926632251PublicAssets/7003
    Catalase diversity
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    Catalase diversity

    7003

    Catalases are some of the most efficient enzymes found in cells. Each catalase molecule can decompose millions of hydrogen peroxide molecules every second—working as an antioxidant to protect cells from the dangerous form of reactive oxygen. Different cells build different types of catalases. The human catalase that protects our red blood cells, shown on the left from PDB entry 1QQW, is composed of four identical subunits and uses a heme/iron group to perform the reaction. Many bacteria scavenge hydrogen peroxide with a larger catalase, shown in the center from PDB entry 1IPH, that uses a similar arrangement of iron and heme. Other bacteria protect themselves with an entirely different catalase that uses manganese ions instead of heme, as shown at the right from PDB entry 1JKU.
    Public NoteThree different colored blobs. Left is pink, yellow and purple and square shaped. Center is pink, yellow, and purple and oval shaped. Right is pink and yellow with green dots and circular.
    Internal NoteFrom: Amy Wu Sent: Thursday, February 1, 2024 4:20 PM To: Bigler, Abbey (NIH/NIGMS) [C] ; Crowley, Rachel (NIH/NIGMS) [E] Cc: Christine Zardecki Subject: [EXTERNAL] RCSB PDB Content for the NIGMS Image and Video Gallery Hi! I hope all is well. Attached is a Google Folder link + Word document with all the requested images and information. Link: https://drive.google.com/drive/folders/17GbO9ddzOn0UAifMihHDo6qAQdIQgE4r?usp=drive_link Please feel free to email me with any questions. Sincerely, Amy Funding Source: RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.
    Keywords
    SourceAmy Wu and Christine Zardecki, RCSB Protein Data Bank.
    Date
    Credit LineDavid S. Goodsell and the RCSB Protein Data Bank.
    Investigator
    Record TypeIllustration
    Topic Area(s);#Molecular Structures;#
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    StatusActive

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