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    Dying melanoma cells
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    Dying melanoma cells

    6966

    Melanoma (skin cancer) cells undergoing programmed cell death, also called apoptosis. This process was triggered by raising the pH of the medium that the cells were growing in. Melanoma in people cannot be treated by raising pH because that would also kill healthy cells. This video was taken using a differential interference contrast (DIC) microscope.
    Public NoteSeveral large round shapes shriveling up and bursting.
    Internal NoteFrom: Burnette, Dylan Tyler dylan.burnette@vanderbilt.edu Sent: Monday, November 14, 2022 9:46 AM To: Bigler, Abbey (NIH/NIGMS) [C] abbey.bigler@nih.gov Subject: [EXTERNAL] Re: NIGMS Gallery Request

    Hi Abbey,

    I would be happy for my images/videos to be added to the NIGMS gallery. Do you need the original versions?

    Dylan 
    Keywords
    SourceDylan T. Burnette, Vanderbilt University School of Medicine.
    Date
    Credit LineDylan T. Burnette, Vanderbilt University School of Medicine.
    InvestigatorThis video shows melanoma cancer cells in culture as they go through programed cell death (apoptosis) as seen through a differential interference contrast (DIC) microscope. Killing cancer cells inside of a human is usually complicated by the need to keep the rest of the cells in the body alive. However, in culture it is more straightforward. In this case, the pH of the medium was raised to a level that triggered apoptosis; not something that would be effective inside a body, as it would also kill a patient’s healthy cells.
    Record TypeVideo
    Topic Area(s);#Cells;#Tools and Techniques;#
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    StatusActive

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