• 24812481119329201240124012146362062024362PublicAssets/6806
    Wild-type and mutant fruit fly ovaries
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    Wild-type and mutant fruit fly ovaries

    6806

    The two large, central, round shapes are ovaries from a typical fruit fly (Drosophila melanogaster). The small butterfly-like structures surrounding them are fruit fly ovaries where researchers suppressed the expression of a gene that controls microtubule polymerization and is necessary for normal development. This image was captured using a confocal laser scanning microscope.

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    Internal NoteAlt text: Two large, round shapes that are touching in the middle and are surrounded by smaller butterfly-like structures. Drosophila melanogaster (fruit fly) wild-type ovaries (big ovaries in the center) and mini spindles (msps) mutant ovaries (small ovaries on the periphery). Mini spindles encodes a Drosophila homolog of XMAP215 and controls microtubule polymerization. Knockdown of msps by a germline-specific RNAi leads to defects of ovary development. Actin filaments were labeled with rhodamine-conjugated phalloidin (red), and DNA was labeled with DAPI (blue). The images were acquired on a Nikon A1plus scanning confocal microscope with a GaAsP detector and a 20X 0.75 N.A. lens using Galvano scanning controlled by Nikon Elements software and assembled by Adobe Illustrator. Dear Abbey, We have some images for you. Would you like to have a look at them? How do you want me to share them with you (TIFF files are too big for email). Best, Vladimir Gelfand
    KeywordsOvary, research organisms
    SourceVladimir I. Gelfand, Feinberg School of Medicine, Northwestern University.
    Date
    Credit LineWen Lu and Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University.
    Investigator
    Record TypePhotograph
    Topic Area(s);#Cells;#Genes;#Tools and Techniques;#
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    StatusActive

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