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    Human endoplasmic reticulum membrane protein complex
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    Human endoplasmic reticulum membrane protein complex

    6777

    A 3D model of the human endoplasmic reticulum membrane protein complex (EMC) that identifies its nine essential subunits. The EMC plays an important role in making membrane proteins, which are essential for all cellular processes. This is the first atomic-level depiction of the EMC. Its structure was obtained using single-particle cryo-electron microscopy.
    Public Note
    Internal NoteRelated to the Science paper “Structural basis for membrane insertion by the human ER membrane protein complex”: https://doi.org/10.1126/science.abb5008
    KeywordsER, cryo-EM
    SourceRebecca Voorhees, California Institute of Technology.
    Date
    Credit LineGiovani Pinton Tomaleri, Voorhees Laboratory, California Institute of Technology.
    Investigator
    Record TypeVideo
    Topic Area(s);#Cells;#Molecular Structures;#Tools and Techniques;#
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    StatusActive

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