• 12006751637156600337184783001684395PublicAssets/6769
    Culex quinquefasciatus mosquito larva
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    Culex quinquefasciatus mosquito larva

    6769

    A mosquito larva with genes edited by CRISPR. The red-orange glow is a fluorescent protein used to track the edits. This species of mosquito, Culex quinquefasciatus, can transmit West Nile virus, Japanese encephalitis virus, and avian malaria, among other diseases. The researchers who took this image developed a gene-editing toolkit for Culex quinquefasciatus that could ultimately help stop the mosquitoes from spreading pathogens. The work is described in the Nature Communications paper "Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes" by Feng et al. Related to image 6770 and video 6771.
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    Internal NoteRelated to the Nature Communications paper “Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes”: https://www.nature.com/articles/s41467-021-23239-0 Permission email: Written permission for inclusion in the NIGMS Image and Video Gallery. Please confirm the material is free of copyright restrictions. Yes, I approve. I personally generated the images/videos and there is no copyright on them. High-resolution file(s) in standard formats (jpeg, png, or tiff for images; mp4 for videos). Here is a Dropbox link where you can have access to higher resolution images. Additionally you will have access to another video and another image: https://www.dropbox.com/sh/hn0f26kxx9qmh9p/AAAj6DKSX1pMEHqr0Au7qTsAa?dl=0 The type of camera/microscope used to capture each image or video. The zoomed in images (green-ish background) were taken with a Canon Rebel T7i camera on a Leica SMZ25 Stereo-microscope. The images taken from the side (where you can see the surface of the water) were taken with a Canon Rebel T7i camera. Any edits needed to make the attached titles, descriptions, and credit information accurate. I added minor edits using track changes in the document you sent. Please let me know if you want more feedback after adding/changing any image.
    KeywordsInsects, bugs, larvae
    SourceValentino Gantz, University of California, San Diego.
    Date
    Credit LineGantz Lab, University of California, San Diego.
    Investigator
    Record TypePhotograph
    Topic Area(s);#Genes;#Injury and Illness;#Tools and Techniques;#
    Previous Uses
    StatusActive

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