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View Entry | Fruit fly nurse cells during egg development6753| In many animals, the egg cell develops alongside sister cells. These sister cells are called nurse cells in the fruit fly (Drosophila melanogaster), and their job is to “nurse” an immature egg cell, or oocyte. Toward the end of oocyte development, the nurse cells transfer all their contents into the oocyte in a process called nurse cell dumping. This process involves significant shape changes on the part of the nurse cells (blue), which are powered by wavelike activity of the protein myosin (red). This image was captured using a confocal laser scanning microscope. Related to video 6754. | | Public Note | | | | | Internal Note | | Related to the PNAS paper “Dynamics of hydraulic and contractile wave-mediated fluid transport during Drosophila oogenesis.” https://doi.org/10.1073/pnas.2019749118
MIT press release: https://news.mit.edu/2021/study-reveals-how-egg-cells-get-so-big-0304
Permission email:
From: Adam C Martin
Sent on: Wednesday, March 17, 2021 12:46:56 AM
To: Abbey Bigler
Subject: FW: NIGMS image and video
Attachments: NIGMS Gallery.docx (14.87 KB)
Hi Abbey,
Thanks for the reminder. Attached is permission, title, and caption for one of the images and a movie from our work funded by NIGMS. The image/movie files are linked below. Let me know if these don’t work for you and I can download and share in a Dropbox folder. Also, let me know if you need more info.
Best,
Adam
Images for the NIGMS image and video gallery
For the image and video below:
Credit Information: Jasmin Imran Alsous and Jonathan Jackson from Adam C. Martin’s lab (Biology Department, MIT)
Permission: We grant permission for inclusion in the NIGMS Image and Video Gallery and confirm that the material is free of copyright restrictions.
Image 1
Title: Myosin activity drives dynamic cell deformations during oogenesis
Caption: Across many animals, the egg cell develops alongside other sister cells. In the fruit fly, Drosophila melanogaster, these sister cells are called nurse cells, and their job is to ‘nurse’ the developing oocyte. Towards the end of oogenesis, the nurse cells transfer all their contents into the oocyte in a process called ‘nurse cell dumping’ to prepare the oocyte for fertilization; this process involves significant shape deformations on part of the nurse cells (cyan), which are powered by wave-like myosin activity (red). This image shows the cluster of nurse cells amidst transport: Note the unusual cell body shapes and cortical myosin activity!
Video 1
Title: Myosin activity drives dynamic cell deformations during oogenesis
Caption: Across many animals, the egg cell develops alongside other sister cells. In the fruit fly, Drosophila melanogaster, these sister cells are called nurse cells, and their job is to ‘nurse’ the developing oocyte. Towards the end of oogenesis, the nurse cells transfer all their contents into the oocyte in a process called ‘nurse cell dumping’ to prepare the oocyte for fertilization; this process involves significant shape deformations on part of the nurse cells (cyan), which are powered by wave-like myosin activity (red). This video captures the nurse cells amidst transport: Note the unusual cell body shapes and wave-like myosin activity! | | | Keywords | | Oogenesis | | | Source | | Adam C. Martin, Massachusetts Institute of Technology. | | | Date | | | | | Credit Line | | Jasmin Imran Alsous and Jonathan Jackson, Martin Lab, Massachusetts Institute of Technology. | | | Investigator | | | | | Record Type | | Photograph | | | Topic Area(s) | | ;#Cells;#Tools and Techniques;# | | | Previous Uses | | | | | Status | | Active | |
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