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    Stress Response in Cells
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    Stress Response in Cells

    6570

    Two highly stressed osteosarcoma cells are shown with a set of green droplet-like structures followed by a second set of magenta droplets. These droplets are composed of fluorescently labeled stress-response proteins, either G3BP or UBQLN2 (Ubiquilin-2). Each protein is undergoing a fascinating process, called phase separation, in which a non-membrane bound compartment of the cytoplasm emerges with a distinct environment from the surrounding cytoplasm. Subsequently, the proteins fuse with like proteins to form larger droplets, in much the same way that raindrops merge on a car’s windshield.
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    SourceJulia F. Riley and Carlos A. Castañeda, Syracuse University
    Date
    Credit LineJulia F. Riley, Heidi Hehnly, Sandra Hewett, and Carlos A. Castañeda, Syracuse University.
    Investigator
    Record TypeVideo
    Topic Area(s);#Cells;#
    Previous Uses
    StatusActive

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