• 16347453230038153723994040718610105PublicAssets/6489
    CRISPR Illustration Frame 5
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    CRISPR Illustration Frame 5

    6489

    This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. This is the fifthframe in a series of five. The CRISPR system has two components joined together: a finely tuned targeting device (a small strand of RNA programmed to look for a specific DNA sequence) and a strong cutting device (an enzyme called Cas9 that can cut through a double strand of DNA). For an explanation and overview of the CRISPR-Cas9 system, see the NIGMS Biomedical Beat blog entry, Field Focus: Precision Gene Editing with CRISPR and the iBiology video, Genome Engineering with CRISPR-Cas9: Birth of a Breakthrough Technology.
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    Internal Notecreated for NIGMS by Crabtree & Co. Jennifer Doudna OK'ed it
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    Date2015-12-16 00:00:00
    Credit LineNational Institute of General Medical Sciences, National Institutes of Health
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    Record TypeIllustration
    Topic Area(s);#Genes;#Tools and Techniques;#
    Previous UsesBioBeat
    StatusActive

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