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    STORM image of axonal cytoskeleton
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    STORM image of axonal cytoskeleton

    3678

    This image shows the long, branched structures (axons) of nerve cells. Running horizontally across the middle of the photo is an axon wrapped in rings made of actin protein (green), which plays important roles in nerve cells. The image was captured with a powerful microscopy technique that allows scientists to see single molecules in living cells in real time. The technique is called stochastic optical reconstruction microscopy (STORM). It is based on technology so revolutionary that its developers earned the 2014 Nobel Prize in Chemistry. More information about this image can be found in: K. Xu, G. Zhong, X. Zhuang. Actin, spectrin and associated proteins form a periodic cytoskeleton structure in axons. Science 339, 452-456 (2013).
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    Internal NoteAnother option is attached. It's from Xiaowei Zhuang, and we have permission to use it. Caption info: STORM_6: STORM image of a novel periodic, actin-spectrin based cytoskeleton in axons. The image shows the STORM image of actin in neurites. The neurite in the middle is an axon, which shows a periodic distribution of actin. Actin filaments and spectrin tetramers interconnect to form a periodic lattice structure that wraps around the circumference of the axon underneath the axonal membrane. [credit the Xiaowei Zhuang laboratory, Howard Hughes Medical Institute, Harvard University]
    Keywords
    SourceXiaowei Zhuang Laboratory, Howard Hughes Medical Institute, Harvard University
    Date2014-11-18 00:00:00
    Credit LineXiaowei Zhuang Laboratory, Howard Hughes Medical Institute, Harvard University
    InvestigatorXiaowei Zhuang
    Record TypePhotograph
    Topic Area(s);#Cells;#Tools and Techniques;#
    Previous UsesGov Delivery Dec 2014
    StatusActive

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