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    Taste Buds
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    Taste Buds

    3444

    Taste buds in a circumvallate papilla in a mouse tongue with types I, II and III taste cells visualized by cell-type-specific fluorescent antibodies. Type II cells respond to sweet, bitter, and umami tastes by signaling to the central nervous system by non-vesicular ATP release. Taruno and colleagues have identified CALHM1 as a voltage-gated ATP release channel that mediates this response to these taste modalities. The work was published in Nature (14 March 2013) and supported in part by the National Institutes of Health (GM56328, MH059937, NS072775, DC10393, EY13624, R03DC011143, P30 EY001583, P30DC011735). A news release about the work can be read here.
    Public Note
    Internal NoteFrom: Kreeger, Karen [mailto:Karen.Kreeger@uphs.upenn.edu] Sent: Wednesday, April 10, 2013 11:57 AM To: Machalek, Alisa Zapp (NIH/NIGMS) [E] Subject: RE: taste buds image--permission to add to image gallery? Hi Alisa. It's been so long since we connected. I hope you are well. We're swamped here with regular requests and the Philadelphia Science Festival. Thanks for your interest in Dr. Foskett?s work. I'm sure it would be OK to use the image, as long as you use the image credit here in the release: http://www.uphs.upenn.edu/news/News_Releases/2013/03/foskett/ Please also send the link when it's ready. I will share with Dr. Foskett. I hope this helps. Cheers, Karen From: Machalek, Alisa Zapp (NIH/NIGMS) [E] [mailto:MachaleA@nigms.nih.gov] Sent: Tuesday, April 09, 2013 4:45 PM To: Kreeger, Karen Subject: taste buds image--permission to add to image gallery? Hi Karen, How goes it? Still doing fine science writing in Philly, I see. As you may know, we're featuring your release about Kevin Foskett's work as a Research Advance slide on the NIGMS website (slide 4). I'd also like to add that gorgeous image to the NIGMS image and video gallery and possibly feature it in various NIGMS publications. Do we have permission to do this? I imagine the image is already in the public domain because of the way it's associated with your release, but I just wanted to check for sure. Hope you're well. With travel funds cut so drastically I don't know when I'll next make it to PA. But if you're ever in the D.C. area, let me know and we can meet up. Best, Alisa
    KeywordsMouth
    Source
    Date2013-04-09 00:00:00
    Credit LineAki Taruno, Perelman School of Medicine, University of Pennsylvania; Nature
    Investigator
    Record TypePhotograph
    Topic Area(s);#Cells;#
    Previous Uses
    StatusActive

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