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    Structure of Glutamate Dehydrogenase
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    Structure of Glutamate Dehydrogenase

    3421

    Some children are born with a mutation in a regulatory site on this enzyme that causes them to over-secrete insulin when they consume protein. We found that a compound from green tea (shown in the stick figure and by the yellow spheres on the enzyme) is able to block this hyperactivity when given to animals with this disorder.
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    Internal NoteRecord of permission to use both of these: Hello Dr. Machalek, I am writing in response to a request from Dr. Gerratana for high resolution images in the chemistry field. We have some very nice photos of opium poppy and other poppy species being studied here at the Donald Danforth Plant Science Center in St. Louis. The PI is Dr. Toni Kutchan, a biochemist, who studies chemical pathways to plant natural product production. If you are interested in these images please let me know. We would be happy to share them. Take care, Judy
    KeywordsGDH, trimers
    SourceJudy Coyle, Donald Danforth Plant Science Center
    Date2012-09-17 00:00:00
    Credit LineThomas Smith, Donald Danforth Plant Science Center
    Investigator
    Record TypePhotograph
    Topic Area(s);#Molecular Structures;#
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    StatusActive

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