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    Nucleosome
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    Nucleosome

    2741

    Like a strand of white pearls, DNA wraps around an assembly of special proteins called histones (colored) to form the nucleosome, a structure responsible for regulating genes and condensing DNA strands to fit into the cell's nucleus. Researchers once thought that nucleosomes regulated gene activity through their histone tails (dotted lines), but a 2010 study revealed that the structures' core also plays a role. The finding sheds light on how gene expression is regulated and how abnormal gene regulation can lead to cancer.
    Public Note
    Internal Notehttp://publications.nigms.nih.gov/biobeat/10-05-19/index.html#1
    KeywordsDNA, DNA packaging, genetics, proteins, cell
    SourceKarolin Luger, Colorado State University
    Date2010-06-10 00:00:00
    Credit LineKarolin Luger, Colorado State University
    InvestigatorKarolin Luger, Colorado State University
    Record TypeIllustration
    Topic Area(s);#Cells;#Genes;#Molecular Structures;#
    Previous UsesBiomedical Beat: May 19, 2010
    StatusActive

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