• 90177680204451388212772161867954PublicAssets/2601
    Mouse liver labeled with fluorescent probe
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    Mouse liver labeled with fluorescent probe

    2601

    A mouse liver glows after being tagged with specially designed infrared-fluorescent protein (IFP). Since its discovery in 1962, green fluorescent protein (GFP) has become an invaluable resource in biomedical imaging. But because of its short wavelength, the light that makes GFP glow doesn't penetrate far in whole animals. So University of California, San Diego cell biologist Roger Tsien--who shared the 2008 Nobel Prize in chemistry for groundbreaking work with GFP--made infrared-fluorescent proteins (IFPs) that shine under longer-wavelength light, allowing whole-body imaging in small animals.
    Public Note
    Internal Notehttp://publications.nigms.nih.gov/biobeat/09-06-18/index.html#3
    Keywords
    SourceXiaokun Shu, University of California, San Diego
    Date2009-06-19 00:00:00
    Credit LineXiaokun Shu, University of California, San Diego
    InvestigatorRoger Tsien, University of California, San Diego
    Record TypePhotograph
    Topic Area(s);#Cells;#Molecular Structures;#Tools and Techniques;#
    Previous UsesBiomedical Beat: June 18, 2009
    StatusActive

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