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    Ubiquitin-fold modifier 1 from C. elegans
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    Ubiquitin-fold modifier 1 from C. elegans

    2388

    Solution NMR structure of protein target WR41 (left) from C. elegans. Noting the unanticipated structural similarity to the ubiquitin protein (Ub) found in all eukaryotic cells, researchers discovered that WR41 is a Ub-like modifier, ubiquitin-fold modifier 1 (Ufm1), on a newly uncovered ubiquitin-like pathway. Subsequently, the PSI group also determined the three-dimensional structure of protein target HR41 (right) from humans, the E2 ligase for Ufm1, using both NMR and X-ray crystallography.
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    Keywordsmodel
    SourceNortheast Structural Genomics Consortium
    Date2007-12-10 00:00:00
    Credit LineNortheast Structural Genomics Consortium
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    Record TypeIllustration
    Topic Area(s);#Molecular Structures;#
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    StatusActive

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