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3580609Industrious V. cholerae bacteria (yellow) tend to thrive in denser biofilms (left) while moochers (red) thrive in weaker biofilms (right). More information about the research behind this image can be found in a <a href="http://biobeat.nigms.nih.gov/2014/02/cool-image-denying-microbial-moochers/">Biomedical Beat Blog posting</a> from February 2014.10/5/2020 6:16:25 AM10/5/2020 6:16:25 AMType    Name    Media Type    File Size    Modified V_M._cholerae_biofilms_32    Medium 50 KB 6/3/2016 3:32 PM aamishral2 (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx197120https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{21F937D8-3F14-4784-AC98-9E76BB4A34A8}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2753491<i>Xenopus laevis</i>, the African clawed frog, has long been used as a model organism for studying embryonic development. In this image, RNA encoding the transcription factor Sox 7 (dark blue) is shown to predominate at the vegetal pole, the yolk-rich portion, of a <i>Xenopus laevis</i> frog egg. Sox 7 protein is important to the regulation of embryonic development.8/21/2020 6:05:59 PM8/21/2020 6:05:59 PMType    Name    Media Type    File Size    Modified Klym1_S    Low 9 KB 9/7/2016 6:11 PM Varkala, Venkat (NIH/NIGMS) [C AZM obtained this image from Dr. Klymkowsky in response to STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12780https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{B5EE0511-C0B1-4806-84BD-E68B638129AB}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
127894Two models for how material passes through the Golgi apparatus: the vesicular shuttle model and the cisternae maturation model. You can see animations of the two different models at <a href="http://publications.nigms.nih.gov/insidethecell/extras/" target="_blank">http://publications.nigms.nih.gov/insidethecell/extras/</a>. Appears in the NIGMS booklet <a href="http://publications.nigms.nih.gov/insidethecell/" target="_blank"><i>Inside the Cell</i></a>.10/28/2020 4:37:04 PM10/28/2020 4:37:04 PMType    Name    Media Type    File Size    Modified ITC_GolgiTheories_S    Low 69 KB 8/24/2016 5:17 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx134110https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{8338FE7B-DE3A-4BB1-9AD3-842F7470380D}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2380316Model of an enzyme, PanB, from <i>Mycobacterium tuberculosis</i>, the bacterium that causes most cases of tuberculosis. This enzyme is an attractive drug target.10/29/2020 4:44:22 PM10/29/2020 4:44:22 PMType    Name    Media Type    File Size    Modified hi_Rv2225_L    Low 53 KB 6/3/2016 3:10 PM aamishral2 (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx142130https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{598D1C54-0A52-4388-8B15-9D8F0CAD6996}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2542405DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. The bases in DNA nucleotides are adenine, thymine, cytosine, and guanine. Featured in <a href=http://publications.nigms.nih.gov/thenewgenetics/ target="_blank"><i>The New Genetics</i></a>.3/4/2022 7:49:23 PM3/4/2022 7:49:23 PMType    Name    Media Type    File Size    Modified Nucleotides_with_labels_S    Low 69 KB 8/24/2016 5:05 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx285170https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{D1C5A0E0-9E8D-476E-BB68-F21AA185C7FA}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3332384Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Recent research has shown that an actin-polymerizing factor called the Arp2/3 complex is the key component of the actin polymerization engine that drives amoeboid cell motility. ARPC3, a component of the Arp2/3 complex, plays a critical role in actin nucleation. In this photo, the ARPC3+/+ fibroblast cells were fixed and stained with Alexa 546 phalloidin for F-actin (red) and DAPI to visualize the nucleus (blue). ARPC3+/+ fibroblasts cells with lamellipodia leading edge. Related information available in a Stowers Institute <a href=http://www.stowers.org/media/news/apr-9-2012 target="_blank"> news release</a>. This image is part of a series of images; related to <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3328">image 3328</a> , <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3329">image 3329</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3330">image 3330</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3331">image 3331</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3333">image 3333</a>.12/23/2020 5:30:53 PM12/23/2020 5:30:53 PMType    Name    Media Type    File Size    Modified Pic-_5a_2_rs_S    Low 6 KB 3/23/2021 11:49 AM Walter, Taylor (NIH/NIGMS) [C In this photo, the ARPC3+/+ fibroblast cells were fixed and stained with STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx10560https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{594A54CB-CF70-4918-B9C1-672340343B0C}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3406394Phenylalanine tRNA showing the anticodon (yellow) and the amino acid, phenylalanine (blue and red spheres). The structure of phenylalanine tRNA is described in this journal article: Kristensen O, Reshetnikova L, Nissen P, Siboska G, Thirup S, Nyborg J. FEBS Lett. 1996 Dec 9;399(1-2):59-62.12/23/2020 8:47:36 PM12/23/2020 8:47:36 PMType    Name    Media Type    File Size    Modified -tRNAPhe-highres_S    Low 37 KB 9/14/2016 11:42 AM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13260https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{EF0971C4-B0FB-4781-9F31-720C0414208A}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6532941In the worm <i>C. elegans</i>, double-stranded RNA made in neurons can silence matching genes in a variety of cell types through the transport of RNA between cells. The head region of three worms that were genetically modified to express a fluorescent protein were imaged and the images were color-coded based on depth. The worm on the left lacks neuronal double-stranded RNA and thus every cell is fluorescent. In the middle worm, the expression of the fluorescent protein is silenced by neuronal double-stranded RNA and thus most cells are not fluorescent. The worm on the right lacks an enzyme that amplifies RNA for silencing. Surprisingly, the identities of the cells that depend on this enzyme for gene silencing are unpredictable. As a result, worms of identical genotype are nevertheless random mosaics for how the function of gene silencing is carried out. For more, see <a href="https://academic.oup.com/nar/article/47/19/10059/5563947">journal article</a> and <a href="https://umdrightnow.umd.edu/news/umd-scientists-discover-hidden-differences-may-help-cells-evade-drug-therapy">press release.</a> Related to image <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6534">6534</a>.12/21/2020 7:45:16 PM12/21/2020 7:45:16 PMType    Name    Media Type    File Size    Modified The_Three_Pharingos_4_flipped_Thumbnail    Thumbnail 94 KB 12/17/2019 2:28 PM Harris, Donald (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx14160https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{818BAE61-BA6A-412E-9A1A-F5BEE4D08EA6}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3265438Microfluidic chips have many uses in biology labs. The one shown here was used by bioengineers to study bacteria, allowing the researchers to synchronize their fluorescing so they would blink in unison. See also entries 3266-3268. From a UC San Diego <a href=http://ucsdnews.ucsd.edu/pressreleases/researchers_create_living_neon_signs_composed_of_millions_of_glowing_bacter/ target="_blank">news release</a>, "Researchers create living 'neon signs' composed of millions of glowing bacteria."12/22/2020 5:19:18 PM12/22/2020 5:19:18 PMType    Name    Media Type    File Size    Modified Hasty1_M    Medium 195 KB 7/27/2016 11:37 AM Varkala, Venkat (NIH/NIGMS) [C The one shown here was used by STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12660https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{069FB04C-35F9-4BC5-A6B3-D4D66C915BBF}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6886922Neutrophil-like cells (blue) in a microfluidic chip preferentially migrating toward LTB4 over fMLP. A neutrophil is a type of white blood cell that is part of the immune system and helps the body fight infection. Both LTB4 and fMLP are molecules involved in immune response. Microfluidic chips are small devices containing microscopic channels, and they are used in a range of applications, from basic research on cells to pathogen detection. The scale bar in this video is 500μm.4/1/2022 8:13:40 PM4/1/2022 8:13:40 PMType    Name    Media Type    File Size    Modified CellMigration    High 3903 KB 4/4/2022 10:32 AM Bigler, Abbey (NIH/NIGMS) [C The scale bar in this video is 500μm STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12760https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{2FB4E3AD-9AC0-4E23-9872-B4D8B3D37E23}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2596349In the top snapshots, the brain of a sleep-deprived fruit fly glows orange, marking high concentrations of a synaptic protein called Bruchpilot (BRP) involved in communication between neurons. The color particularly lights up brain areas associated with learning. By contrast, the bottom images from a well-rested fly show lower levels of the protein. These pictures illustrate the results of an April 2009 study showing that sleep reduces the protein's levels, suggesting that such "downscaling" resets the brain to normal levels of synaptic activity and makes it ready to learn after a restful night. Featured in the May 20, 2009, issue of <a href=http://publications.nigms.nih.gov/biobeat/09-05-20/index.html#1 target="_blank"><em>Biomedical Beat</em></a>.10/30/2020 7:21:43 PM10/30/2020 7:21:43 PMType    Name    Media Type    File Size    Modified sleep_fly1_L    Low 9 KB 6/3/2016 3:13 PM aamishral2 (NIH/NIGMS) [C These pictures illustrate the results of an April 2009 study showing that sleep reduces the protein's levels STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12070https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{179D8D15-FAF6-4541-9811-87052DBCC0B8}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6993890RNA polymerase (purple) is a complex enzyme at the heart of transcription. During this process, the enzyme unwinds the DNA double helix and uses one strand (darker orange) as a template to create the single-stranded messenger RNA (green), later used by ribosomes for protein synthesis. <Br><Br> From the <a href="https://www.rcsb.org/structure/1i6h">RNA polymerase II elongation complex of <em>Saccharomyces cerevisiae</em></a> (PDB entry 1I6H) as seen in PDB-101's <a href="https://pdb101.rcsb.org/learn/videos/what-is-a-protein-video">What is a Protein?</a> video. 2/2/2024 8:58:06 PM2/2/2024 8:58:06 PMType    Name    Media Type    File Size    Modified RNA Polymerase_M    Medium 94 KB 2/2/2024 3:00 PM Crowley, Rachel (NIH/NIGMS) [E STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx132100https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{71AFD580-3D70-478C-AEC2-EA8919D965A0}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3644753Just 22 hours after fertilization, this zebrafish embryo is already taking shape. By 36 hours, all of the major organs will have started to form. The zebrafish's rapid growth and see-through embryo make it ideal for scientists studying how organs develop. This image is part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.11/28/2022 9:47:40 PM11/28/2022 9:47:40 PMType    Name    Media Type    File Size    Modified 10_2_ZebrafishEmbryo    High 3224 KB 11/25/2020 11:08 AM Walter, Taylor (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12580https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{EFC93598-A9C4-4712-A66F-7BB63D0EAD93}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
7004982Protein kinases—enzymes that add phosphate groups to molecules—are cancer chemotherapy targets because they play significant roles in almost all aspects of cell function, are tightly regulated, and contribute to the development of cancer and other diseases if any alterations to their regulation occur. Genetic abnormalities affecting the c-Abl tyrosine kinase are linked to chronic myelogenous leukemia, a cancer of immature cells in the bone marrow. In the noncancerous form of the protein, binding of a myristoyl group to the kinase domain inhibits the activity of the protein until it is needed (top left shows the inactive form, top right shows the open and active form). The cancerous variant of the protein, called Bcr-Abl, lacks this autoinhibitory myristoyl group and is continually active (bottom). ATP is shown in green bound in the active site of the kinase. <Br><Br> Find these in the RCSB Protein Data Bank: <a href="https://www.rcsb.org/structure/1OPL">c-Abl tyrosine kinase and regulatory domains</a> (PDB entry 1OPL) and <a href="https://www.rcsb.org/structure/1ZZP">F-actin binding domain</a> (PDB entry 1ZZP). 2/12/2024 9:07:10 PM2/12/2024 9:07:10 PMType    Name    Media Type    File Size    Modified bcr-abl_M    Medium 149 KB 2/5/2024 8:29 AM Crowley, Rachel (NIH/NIGMS) [E In the noncancerous form of the STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx206130https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{5A8F2830-6D55-4A9A-AB75-D62F62FCEE45}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
127592The Golgi complex, also called the Golgi apparatus or, simply, the Golgi. This organelle receives newly made proteins and lipids from the ER, puts the finishing touches on them, addresses them, and sends them to their final destinations. Appears in the NIGMS booklet <a href="http://publications.nigms.nih.gov/insidethecell/" target="_blank"><i>Inside the Cell</i></a>.10/28/2020 4:29:29 PM10/28/2020 4:29:29 PMType    Name    Media Type    File Size    Modified ITC_Golgi_inset_Copy_M    Medium 28 KB 10/28/2020 12:29 PM McCulley, Jennifer (NIH/NIDCD) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx4102170https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{F1ACB139-25A3-4C54-8EE3-575084FC6DB6}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6810917Three fruit fly (<em>Drosophila melanogaster</em>) ovarioles (yellow, blue, and magenta) with egg cells visible inside them. Ovarioles are tubes in the reproductive systems of female insects. Egg cells form at one end of an ovariole and complete their development as they reach the other end, as shown in the yellow wild-type ovariole. This process requires an important protein that is missing in the blue and magenta ovarioles. This image was created using confocal microscopy. <Br><Br> More information on the research that produced this image can be found in the <em> Current Biology</em> paper <a href="https://www.cell.com/current-biology/fulltext/S0960-9822(21)00669-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982221006692%3Fshowall%3Dtrue">“Gatekeeper function for Short stop at the ring canals of the <em>Drosophila</em> ovary”</a> by Lu et al. 1/21/2022 3:51:54 PM1/21/2022 3:51:54 PMType    Name    Media Type    File Size    Modified Fruit fly ovarioles_6810_M    Medium 290 KB 2/11/2022 2:16 PM Dolan, Lauren (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx15170https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{C9C95BC4-65E6-4B68-BC4A-814E3F8B69D5}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2784364Cytoplasmic linker protein (CLIP)-170 is a microtubule plus-end-tracking protein that regulates microtubule dynamics and links microtubule ends to different intracellular structures. In this movie, the gene for CLIP-170 has been fused with green fluorescent protein (GFP). When the protein is expressed in cells, the activities can be monitored in real time. Here, you can see CLIP-170 streaming towards the edges of the cell.9/4/2020 7:36:43 PM9/4/2020 7:36:43 PMType    Name    Media Type    File Size    Modified 2784_Microtubule_dynamics_in_real_time_S    Low 61 KB 3/29/2019 10:52 AM Constantinides, Stephen (NIH/NIGMS STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13460https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{4781051C-2EC7-46D6-95BC-529D28314966}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3627806The parasitic worm that causes schistosomiasis hatches in water and grows up in a freshwater snail, as shown here. Once mature, the worm swims back into the water, where it can infect people through skin contact. Initially, an infected person might have a rash, itchy skin or flu-like symptoms, but the real damage is done over time to internal organs. This image is part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.11/22/2022 7:53:32 PM11/22/2022 7:53:32 PMType    Name    Media Type    File Size    Modified 8B_larvae_schistosomiasis (1) (1)    High 1940 KB 11/20/2020 5:15 PM Walter, Taylor (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx11360https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{295888E1-6943-49B5-B00A-3FC02A2C423E}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6579993A 3D reconstruction, created using cryo-electron microscopy, of an ion channel known as the full-length serotonin receptor in complex with the antinausea drug granisetron (orange). Ion channels are proteins in cell membranes that help regulate many processes.8/11/2020 12:09:34 AM8/11/2020 12:09:34 AMType    Name    Media Type    File Size    Modified SerotininReceptor2_thumb    Thumbnail 19 KB 8/18/2020 12:31 AM Harris, Donald (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12770https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{5C7B5894-2DC6-4625-A256-DC9803ECE5CE}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
101288A light microscope image of a cell from the endosperm of an African globe lily (<i>Scadoxus katherinae</i>). This is one frame of a time-lapse sequence that shows cell division in action. The lily is considered a good organism for studying cell division because its chromosomes are much thicker and easier to see than human ones. Staining shows microtubules in red and chromosomes in blue.5/9/2022 1:42:46 PM5/9/2022 1:42:46 PMType    Name    Media Type    File Size    Modified lilymit2_S    Low 13 KB 9/8/2016 2:28 PM Varkala, Venkat (NIH/NIGMS) [C A light microscope image of a cell from the endosperm of an African STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx14650https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{C8B137B6-B281-434D-A7DA-DDF119C39F2F}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2377122Model of a protein involved in cell division from <i>Mycoplasma pneumoniae</i>. This model, based on X-ray crystallography, revealed a structural domain not seen before. The protein is thought to be involved in cell division and cell wall biosynthesis.10/29/2020 4:40:17 PM10/29/2020 4:40:17 PMType    Name    Media Type    File Size    Modified 2377_th_psi_image_ring1_M    Medium 86 KB 3/12/2019 11:51 AM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12450https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{1DD19568-AE11-4614-8771-B2DA2A46AAC6}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2412128Crystals of porcine alpha amylase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.8/6/2020 7:43:47 PM8/6/2020 7:43:47 PMType    Name    Media Type    File Size    Modified f07Q_pig_alpha_amylase1_S    Low 42 KB 9/7/2016 3:41 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13250https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{E9F19A73-FA71-493E-8C7D-9B1B2ADB206F}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2369186A robot is transferring 96 purification columns to a vacuum manifold for subsequent purification procedures.10/29/2020 4:21:50 PM10/29/2020 4:21:50 PMType    Name    Media Type    File Size    Modified hi_nesg5_3_M    Medium 136 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13250https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{185F3CC9-F9B8-47D6-A04D-4BA2C45C5E0E}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2407194Crystals of jack bean concanavalin A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.8/6/2020 7:30:26 PM8/6/2020 7:30:26 PMType    Name    Media Type    File Size    Modified f06R_jack_bean_concanavalin_A1_S    Low 64 KB 9/7/2016 3:34 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx10650https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{EB3CA1E4-5DA7-49B9-A42F-48BBA94656AD}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2451200Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. In order to fulfill these diverse roles, the timing and location of Cdc42 activation must be tightly controlled. Klaus Hahn and his research group use special dyes designed to report protein conformational changes and interactions, here in living neutrophil cells. Warmer colors in this image indicate higher levels of activation. Cdc42 looks to be activated at cell protrusions.5/9/2022 1:33:37 PM5/9/2022 1:33:37 PMType    Name    Media Type    File Size    Modified filo_cell_1    High 231 KB 6/3/2016 3:11 PM aamishral2 (NIH/NIGMS) [C Warmer colors in this image indicate STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx10550https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{6AC8DB1A-B5E1-462E-9265-2D1A58E2C6F4}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
1101288This image of human red blood cells was obtained with the help of a scanning electron microscope, an instrument that uses a finely focused electron beam to yield detailed images of the surface of a sample.3/13/2023 7:34:30 PM3/13/2023 7:34:30 PMType    Name    Media Type    File Size    Modified RBC.B_W.Carvallo_M    Medium 47 KB 1/28/2021 8:02 AM McCulley, Jennifer (NIH/NIDCD) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx10650https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{F3C64B84-EF6C-4B97-A2A1-0C56130FFA52}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
1286292The membrane that surrounds a cell is made up of proteins and lipids. Depending on the membrane's location and role in the body, lipids can make up anywhere from 20 to 80 percent of the membrane, with the remainder being proteins. Cholesterol (green), which is not found in plant cells, is a type of lipid that helps stiffen the membrane. Appears in the NIGMS booklet <a href="http://publications.nigms.nih.gov/insidethecell/" target="_blank"><i>Inside the Cell</i></a>.10/28/2020 5:12:12 PM10/28/2020 5:12:12 PMType    Name    Media Type    File Size    Modified ITC_Membrane_inset_Copy_M    Medium 94 KB 10/28/2020 1:11 PM McCulley, Jennifer (NIH/NIDCD) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12050https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{8CF4CDB4-39F6-42E4-9789-59241015AA95}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
1291295Sensory organs have cells equipped for detecting signals from the environment, such as odors. Receptors in the membranes of nerve cells in the nose bind to odor molecules, triggering a cascade of chemical reactions tranferred by G proteins into the cytoplasm. Appears in the NIGMS booklet <a href="http://publications.nigms.nih.gov/insidethecell/" target="_blank"><i>Inside the Cell</i></a>.10/28/2020 7:26:43 PM10/28/2020 7:26:43 PMType    Name    Media Type    File Size    Modified ITC_Olf_layout_copy_M    Medium 101 KB 10/28/2020 3:25 PM McCulley, Jennifer (NIH/NIDCD) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx11350https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{59382CB1-C3D0-4E54-8EDE-4D63F420D8B5}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2549341DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). On ribosomes, transfer RNA (tRNA) reads three codons at a time in mRNA to bring together the amino acids that link up to make a protein. See image 2548 for a version of this illustration that isn't numbered and 2547 for a an entirely unlabeled version. Featured in <a href=http://publications.nigms.nih.gov/thenewgenetics/ target="_blank"><i>The New Genetics</i></a>.5/13/2024 6:31:53 PM5/13/2024 6:31:53 PMType    Name    Media Type    File Size    Modified Translation_with_labels_and_stages_M    Medium 115 KB 7/27/2016 11:45 AM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx15150https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{F31244A1-27B7-404B-8A4E-3E8E9AEE63E7}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3402390When the heat shock protein hsp33 is folded, it is inactive and contains a zinc ion, stabilizing the redox sensitive domain (orange). In the presence of an environmental stressor, the protein releases the zinc ion, which leads to the unfolding of the redox domain. This unfolding causes the chaperone to activate by reaching out its "arm" (green) to protect other proteins.12/23/2020 8:26:19 PM12/23/2020 8:26:19 PMType    Name    Media Type    File Size    Modified 3402_Hsp33_Heat_Shock_Protein_Inactive_to_Active_T    Thumbnail 47 KB 3/28/2019 4:30 PM Constantinides STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx11350https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{2962ED30-8F77-47DA-98CF-7B5D57A4BA75}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3327450This 1 1/2-minute video animation was produced for chemical biologist Stuart Schreiber's lab page. Link to video: http://www.broadinstitute.org/chembio/lab_schreiber/anims/animations/smdbFold.php. The animation shows how diverse chemical structures can be produced in the lab.12/23/2020 5:04:14 PM12/23/2020 5:04:14 PMType    Name    Media Type    File Size    Modified PERMISSION: From: Eric Keller [mailto:bloopatone@gmail.com] Sent: Friday, March 30, 2012 11:55 PM To: Machalek, Alisa Zapp (NIH/NIGMS) [E] Subject: Re: seeking STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx11750https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{12226E85-CC5E-44C7-A30F-0836917A55B6}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2536471The G switch allows our bodies to respond rapidly to hormones. See images 2537 and 2538 for labeled versions of this image. Featured in <a href=http://publications.nigms.nih.gov/medbydesign/ target="_blank"><i>Medicines By Design</i></a>.10/9/2020 4:47:14 PM10/9/2020 4:47:14 PMType    Name    Media Type    File Size    Modified The_G_Switch_S    Low 42 KB 8/24/2016 3:09 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx11850https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{D9496E31-4B5E-4424-B18C-CBE535D4C526}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2565476To splice a human gene (in this case, the one for insulin) into a plasmid, scientists take the plasmid out of an E. coli bacterium, cut the plasmid with a restriction enzyme, and splice in insulin-making human DNA. The resulting hybrid plasmid can be inserted into another E. coli bacterium, where it multiplies along with the bacterium. There, it can produce large quantities of insulin. See image 2564 for an unlabeled version of this illustration. Featured in <a href=http://publications.nigms.nih.gov/thenewgenetics/ target="_blank"><i>The New Genetics</i></a>.10/30/2020 3:11:32 PM10/30/2020 3:11:32 PMType    Name    Media Type    File Size    Modified 2565_Recombinant_DNA_with_labels_T    Thumbnail 68 KB 4/19/2019 12:32 PM Constantinides, Stephen (NIH/NIGMS STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12250https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{A780F72F-734F-4D94-81C3-FE59ADC48D86}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2566477Haplotypes are combinations of gene variants that are likely to be inherited together within the same chromosomal region. In this example, an original haplotype (top) evolved over time to create three newer haplotypes that each differ by a few nucleotides (red). See image 2567 for a labeled version of this illustration. Featured in <a href=http://publications.nigms.nih.gov/thenewgenetics/ target="_blank"><i>The New Genetics</i></a>.10/30/2020 3:58:54 PM10/30/2020 3:58:54 PMType    Name    Media Type    File Size    Modified Haplotypes_S    Low 41 KB 8/26/2016 3:18 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13060https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{57CF13EE-EF59-48F7-B0D1-B2EA7353CB87}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3442588These images show three stages of cell division in Xenopus XL177 cells, which are derived from tadpole epithelial cells. They are (from top): metaphase, anaphase and telophase. The microtubules are green and the chromosomes are blue. Related to <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3443">image 3443</a>.8/22/2020 5:25:02 PM8/22/2020 5:25:02 PMType    Name    Media Type    File Size    Modified mitotic1_M    Medium 94 KB 6/3/2016 3:29 PM aamishral2 (NIH/NIGMS) [C These images show three stages of cell division in Xenopus XL177 cells, which are derived from tadpole STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12750https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{385F83B3-C956-487B-9A75-4C353F0A940E}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3489594To develop a system for studying cell motility in unnatrual conditions -- a microscope slide instead of the body -- Tom Roberts and Katsuya Shimabukuro at Florida State University disassembled and reconstituted the motility parts used by worm sperm cells.9/8/2020 11:09:41 PM9/8/2020 11:09:41 PMType    Name    Media Type    File Size    Modified Roberts_cool_image    High 36 KB 6/3/2016 3:30 PM aamishral2 (NIH/NIGMS) [C nih.gov> wrote: Dear Dr. Roberts STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13250https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{56D4D731-F837-44AD-BCAE-9A46C68B1083}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
63896542/3/2020 7:41:16 PM2/3/2020 7:41:16 PMType    Name    Media Type    File Size    Modified Red and white blood cells in lung_M    Medium 484 KB 3/13/2018 4:02 PM Constantinides, Stephen (NIH/NIGMS STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx10950https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{80CC8DC3-7C67-40C7-A007-3A53BB871004}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3479658Using an electrode, researchers apply an electrical pulse onto a piece of muscle tissue affected by Huntington's disease.8/31/2020 4:45:09 AM8/31/2020 4:45:09 AMType    Name    Media Type    File Size    Modified 3479_StagePhoto_for_S    Low 76 KB 3/28/2019 4:21 PM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13650https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{C4F9DEFD-2994-415C-8A90-EE15EAA4AEFB}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3615680Insects like the fruit fly use an elaborate network of branching tubes called trachea (green) to transport oxygen throughout their bodies. Fruit flies have been used in biomedical research for more than 100 years and remain one of the most frequently studied model organisms. They have a large percentage of genes in common with us, including hundreds of genes that are associated with human diseases. This image is part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.11/22/2022 8:52:55 PM11/22/2022 8:52:55 PMType    Name    Media Type    File Size    Modified 5_left_Insect_tracheal_cell_L    Low 180 KB 6/3/2016 3:34 PM aamishral2 (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx10850https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{64887A4A-975E-4460-BF72-BF9D23426499}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3599741This normal human skin cell was treated with a growth factor that triggered the formation of specialized protein structures that enable the cell to move. We depend on cell movement for such basic functions as wound healing and launching an immune response. This image is part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.11/22/2022 9:45:19 PM11/22/2022 9:45:19 PMType    Name    Media Type    File Size    Modified 3_bottom_skin_cell_3600x5400_H    High 2134 KB 3/20/2023 2:54 PM Mills, Matt (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx11750https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{E3B82AA0-A107-4E8D-B950-87E8813CA9EC}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3735762This image shows collagen, a fibrous protein that's the main component of the extracellular matrix (ECM). Collagen is a strong, ropelike molecule that forms stretch-resistant fibers. The most abundant protein in our bodies, collagen accounts for about a quarter of our total protein mass. Among its many functions is giving strength to our tendons, ligaments and bones and providing scaffolding for skin wounds to heal. There are about 20 different types of collagen in our bodies, each adapted to the needs of specific tissues5/13/2024 5:50:36 PM5/13/2024 5:50:36 PMType    Name    Media Type    File Size    Modified Collagen3_L    Low 109 KB 6/3/2016 3:40 PM aamishral2 (NIH/NIGMS) [C There are about 20 different types of STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13350https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{01DAE8CA-F004-4A2C-8DCC-B99B03165816}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3522796Multiphoton fluorescence image of cultured HeLa cells with a fluorescent protein targeted to the Golgi apparatus (orange), microtubules (green) and counterstained for DNA (cyan). Nikon RTS2000MP custom laser scanning microscope. See related images 3518,3519,3520,3521.9/27/2020 3:38:02 AM9/27/2020 3:38:02 AMType    Name    Media Type    File Size    Modified HeLa_cells_1_L    Low 101 KB 6/3/2016 3:30 PM aamishral2 (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13350https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{02904D0C-5907-4F49-8704-9EAD971B040C}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
3690814An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. Image is featured on Biomedical Beat blog post <a href="http://biobeat.nigms.nih.gov/2015/10/cool-image-dna-origami" target=_blank>Cool Image: DNA Origami</a>. See also related <a href="http://images.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3689" target=_blank>image 3689</a> .12/2/2020 7:31:54 PM12/2/2020 7:31:54 PMType    Name    Media Type    File Size    Modified 3690_DNA_origami_micrograph_Dr._Hao_S    Low 86 KB 3/28/2019 4:04 PM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12350https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{3A34011E-6D23-4EE7-B458-423E37A03BCC}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6781869The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. Understanding these processes during healthy development can guide further research into what goes wrong in cases of neuropsychiatric disorders. Also fluorescently labeled in this video are neurons (red) and nuclei (blue). Calling Cards and its application are described in the <em>Cell</em> paper “<a href=https://www.sciencedirect.com/science/article/pii/S009286742030814X>Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells</a>” by Moudgil et al.; and the <em>Proceedings of the National Academy of Sciences</em> paper “<a href=https://www.pnas.org/content/117/18/10003>A viral toolkit for recording transcription factor–DNA interactions in live mouse tissues</a>” by Cammack et al. This video was created for the <em>NIH Director’s Blog</em> post <a href=https://directorsblog.nih.gov/2021/08/24/the-amazing-brain-tracking-molecular-events-with-calling-cards-in-the-living-brain>The Amazing Brain: Tracking Molecular Events with Calling Cards</a>. <Br><Br> Related to image <a href=https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6780>6780</a>.7/17/2023 4:43:08 PM7/17/2023 4:43:08 PMType    Name    Media Type    File Size    Modified mouse-brain-2-720_mp4_hd    Other 21462 KB 9/10/2021 1:14 PM Dolan, Lauren (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12350https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{159782BB-22BC-4404-AACB-1A0649C7AB3B}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6548894Cilia (cilium in singular) are complex molecular machines found on many of our cells. One component of cilia is the doublet microtubule, a major part of cilia’s skeletons that give them support and shape. This animated image is a partial model of a doublet microtubule’s structure based on cryo-electron microscopy images. Video can be found here <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6549"> 6549. </a>12/22/2020 3:28:03 PM12/22/2020 3:28:03 PMType    Name    Media Type    File Size    Modified 18046_Axoneme_Still_Watermark_Thumb    Thumbnail 39 KB 3/19/2020 3:12 PM Harris, Donald (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12150https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{B48B9B01-3F87-4F01-8650-EE6F89E59501}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
1333169Meiosis is used to make sperm and egg cells. During meiosis, a cell's chromosomes are copied once, but the cell divides twice. During mitosis, the chromosomes are copied once, and the cell divides once. For simplicity, cells are illustrated with only three pairs of chromosomes. Appears in the NIGMS booklet <a href="http://publications.nigms.nih.gov/insidethecell/" target="_blank"><i>Inside the Cell</i></a>.12/1/2021 7:25:28 PM12/1/2021 7:25:28 PMType    Name    Media Type    File Size    Modified 1333_ITC_MitoMeio_layout_M    Medium 603 KB 4/19/2019 12:29 PM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13750https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{1FF68C04-833A-4FB0-B984-B82B6C497DD6}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2320239How far and fast an infectious disease spreads across a community depends on many factors, including transportation. These U.S. maps, developed as part of an international study to simulate and analyze disease spread, chart daily commuting patterns. They show where commuters live (top) and where they travel for work (bottom). Green represents the fewest number of people whereas orange, brown, and white depict the most. Such information enables researchers and policymakers to visualize how an outbreak in one area can spread quickly across a geographic region. Featured in the August 15, 2007, issue of <a href=http://publications.nigms.nih.gov/biobeat/07-08-15/#1 target="_blank"><em>Biomedical Beat</em></a>.10/29/2020 1:48:39 PM10/29/2020 1:48:39 PMType    Name    Media Type    File Size    Modified 2320_mappingdisease1_S    Low 134 KB 3/29/2019 1:49 PM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13260https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{DCC53428-D85F-4B28-AE7A-1BDF3A1498B7}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6788870Meiosis is used to make sperm and egg cells. During meiosis, a cell's chromosomes are copied once, but the cell divides twice. During mitosis, the chromosomes are copied once, and the cell divides once. For simplicity, cells are illustrated with only three pairs of chromosomes.<Br><Br> See image <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=1333">1333</a> for an unlabeled version of this illustration.1/21/2022 4:01:54 PM1/21/2022 4:01:54 PMType    Name    Media Type    File Size    Modified ITC_MitoMeio_layout (1)_M    Medium 45 KB 12/1/2021 2:08 PM Crowley, Rachel (NIH/NIGMS) [E STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx12850https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{9B45CCDD-6A3A-4182-A4F5-92C942058028}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
6598903When we walk, muscles and nerves interact in intricate ways. This simulation, which is based on data from a six-foot-tall man, shows these interactions.1/28/2021 8:07:12 PM1/28/2021 8:07:12 PMType    Name    Media Type    File Size    Modified Simulation of Leg Muscles Moving    Medium 2554 KB 12/10/2020 5:35 PM Walter, Taylor (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx13150https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{FE1C4F82-744B-4AC6-B161-DAAA9406C8B4}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
2343309This crystal structure shows a conserved hypothetical protein from <i>Mycobacterium tuberculosis</i>. Only 12 other proteins share its sequence homology, and none has a known function. This structure indicates the protein may play a role in metabolic pathways. Featured as one of the August 2007 Protein Structure Initiative Structures of the Month.10/29/2020 2:48:36 PM10/29/2020 2:48:36 PMType    Name    Media Type    File Size    Modified 2343_Mtuberculosis_S    Low 127 KB 3/29/2019 1:42 PM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx15570https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{C049B741-42A1-4298-8E5F-15EE784B48B7}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131