Skip to main content
National Institute of
General Medical Sciences
Facebook
Instagram
Linkedin
Subscriptions
X
YouTube
Research Areas
Areas of Research
Biophysics, Biomedical Technology, and Computational Biosciences
Genetics and Molecular, Cellular, and Developmental Biology
Pharmacology, Physiology, and Biological Chemistry
Research Capacity Building
Training, Workforce Development, and Diversity
Related Information
Contacts by Research Area
Funding Opportunities and Notices
Resources
NIH RePORTER
Research Training
Programs
Dashboard of TWD Funded Programs
High School and Undergraduate Programs
Postbaccalaureate and Graduate Students
Postdoctoral, Early Career, and Faculty
Workforce Developement
Related Information
Contact Information
Division Structure and Programs
Resources
Enhancing Diversity in Training Programs
FAQs About Noncompliance and Withdrawal of Applications
Laboratory Safety and Guidelines
Training Resources
Capacity Building
Division for Research Capacity Building
Institutional Development Award (IDeA)
Native American Research Centers for Health (NARCH)
Science Education Partnership Awards (SEPA)
Support of Competitive Research (SCORE)
Related Information
DRCB News
DRCB Staff Contacts
Resources
NIH RePORTER
Grants and Funding
Funding Opportunities
Current NIGMS Funding Opportunities
Parent Announcements for Investigator-Initiated Applications
Research Funding
Research Project Grants (NIH Parent R01)
Research With Activities Related to Diversity (ReWARD)
Maximizing Investigators' Research Awards (MIRA)
Instrumentation Grant Program for Resource-Limited Institutions (RLI-S10)
Undergraduate-Focused Institutions
Small Business Research
Multidisciplinary Teams/Collaborative Research
Technology Development
Research Resources
Clinical Studies and Trials
Conferences and Scientific Meetings
Administrative Supplements
All Funding Opportunities
Grant Application and Post-Award Information
How to Apply
Grant Application and Review Process
NIGMS Funding Policies
Post-Award Information
Talking to NIH Staff About Your Application and Grant
Considerations for Multiple Principal Investigator (MPI) Applications
Resources
Attribution of NIH/NIGMS Support
Message to NIGMS Investigators
NIH RePORTER
Research Using Human Subjects or Specimens
Science Education
Explore by Topic
Being a Scientist
Cells
Chemistry, Biochemistry, and Pharmacology
Genes
Injury and Illness
Molecular Structures
Tools and Techniques
Explore by Type
Activities and Multimedia
Biomedical Beat Blog
Fact Sheets
Glossary
Order Print Resources
Other Resources
Pathways Teaching Resources
Printable Coloring Pages
STEM Teaching Resources
News and Events
News
News from NIGMS
NIGMS in the News
COVID-19 News
Biomedical Beat Blog
NIGMS Feedback Loop Blog
Meetings and Events
NIGMS-Supported Meetings
Meeting and Programmatic Reports
Webinars for the NIGMS Training Community
Face to Face with Program Directors
Grant Writing Webinar Series for Institutions Building Research and Research Training Capacity
Media Resources
Image and Video Gallery
More Multimedia Resources
About NIGMS
Who We Are
Overview
Director's Corner
Organization and Staff
History
Staff Directory
What We Do
Budget, Financial Management, and Congressional Material
Strategic Plans
Data Integration, Modeling, and Analytics
Advisory Council
Communications and Public Liaison Branch
Work With Us
Job Vacancies
Where We Are
Visitor Information
Image and Video Gallery
>
Search Results
Image and Video Gallery
Research Areas
Areas of Research
Biophysics, Biomedical Technology, and Computational Biosciences
Genetics and Molecular, Cellular, and Developmental Biology
Pharmacology, Physiology, and Biological Chemistry
Research Capacity Building
Training, Workforce Development, and Diversity
Related Information
Contacts by Research Area
Funding Opportunities and Notices
Resources
NIH RePORTER
Research Training
Programs
Dashboard of TWD Funded Programs
High School and Undergraduate Programs
Postbaccalaureate and Graduate Students
Postdoctoral, Early Career, and Faculty
Workforce Developement
Related Information
Contact Information
Division Structure and Programs
Resources
Enhancing Diversity in Training Programs
FAQs About Noncompliance and Withdrawal of Applications
Laboratory Safety and Guidelines
Training Resources
Capacity Building
Division for Research Capacity Building
Institutional Development Award (IDeA)
Native American Research Centers for Health (NARCH)
Science Education Partnership Awards (SEPA)
Support of Competitive Research (SCORE)
Related Information
DRCB News
DRCB Staff Contacts
Resources
NIH RePORTER
Grants and Funding
Funding Opportunities
Current NIGMS Funding Opportunities
Parent Announcements for Investigator-Initiated Applications
Research Funding
Research Project Grants (NIH Parent R01)
Research With Activities Related to Diversity (ReWARD)
Maximizing Investigators' Research Awards (MIRA)
Instrumentation Grant Program for Resource-Limited Institutions (RLI-S10)
Undergraduate-Focused Institutions
Small Business Research
Multidisciplinary Teams/Collaborative Research
Technology Development
Research Resources
Clinical Studies and Trials
Conferences and Scientific Meetings
Administrative Supplements
All Funding Opportunities
Grant Application and Post-Award Information
How to Apply
Grant Application and Review Process
NIGMS Funding Policies
Post-Award Information
Talking to NIH Staff About Your Application and Grant
Considerations for Multiple Principal Investigator (MPI) Applications
Resources
Attribution of NIH/NIGMS Support
Message to NIGMS Investigators
NIH RePORTER
Research Using Human Subjects or Specimens
Science Education
Explore by Topic
Being a Scientist
Cells
Chemistry, Biochemistry, and Pharmacology
Genes
Injury and Illness
Molecular Structures
Tools and Techniques
Explore by Type
Activities and Multimedia
Biomedical Beat Blog
Fact Sheets
Glossary
Order Print Resources
Other Resources
Pathways Teaching Resources
Printable Coloring Pages
STEM Teaching Resources
News and Events
News
News from NIGMS
NIGMS in the News
COVID-19 News
Biomedical Beat Blog
NIGMS Feedback Loop Blog
Meetings and Events
NIGMS-Supported Meetings
Meeting and Programmatic Reports
Webinars for the NIGMS Training Community
Face to Face with Program Directors
Grant Writing Webinar Series for Institutions Building Research and Research Training Capacity
Media Resources
Image and Video Gallery
More Multimedia Resources
About NIGMS
Who We Are
Overview
Director's Corner
Organization and Staff
History
Staff Directory
What We Do
Budget, Financial Management, and Congressional Material
Strategic Plans
Data Integration, Modeling, and Analytics
Advisory Council
Communications and Public Liaison Branch
Work With Us
Job Vacancies
Where We Are
Visitor Information
Related Information
Search Results
Search the NIGMS Image and Video Gallery
Enter Search Keywords
Show Advanced Search Options
Select Type
Photograph
Illustration
Video
Select Topic
Being a Scientist
Cells
Chemistry, Biochemistry, and Pharmacology
Genes
Injury and Illness
Molecular Structures
Tools and Techniques
Select Pixel Options
500
1000
Sort By
Image ID (descending)
Shortest side (ascending)
Shortest side (descending)
Longest side (ascending)
Longest side (descending)
It looks like your browser does not have JavaScript enabled. Please turn on JavaScript and try again.
3438
3370
The chemical structure of the morphine molecule
8/22/2020 4:44:39 PM
8/22/2020 4:44:39 PM
Morphine_
structure
__thumbnail_ Thumbnail 2 KB 6/3/2016 3:29 PM aamishral2 (NIH
Morphine_
structure
_L High 4772 KB 6/3/2016 3:29 PM aamishral2 (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
13
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{6EE205B7-C53B-4A56-B1E5-DB767CF5273F}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2342
3086
X-ray structure of a new DNA repair enzyme superfamily representative from the human gastrointestinal bacterium <i>Enterococcus faecalis</i>. European scientists used this structure to generate homologous structures. Featured as the May 2007 Protein Structure Initiative Structure of the Month.
10/29/2020 2:46:36 PM
10/29/2020 2:46:36 PM
European scientists used this
structure
to generate homologous
structures
Featured as the May 2007 Protein
Structure
Initiative
Structure
of the Month
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
14
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{985DEF74-B19F-428E-A73F-96B3A80C5557}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2363
3150
The goal of the PSI is to determine the three-dimensional shapes of a wide range of proteins by solving the structures of representative members of each protein family found in nature. The collection of structures should serve as a valuable resource for biomedical research scientists.
10/29/2020 4:12:18 PM
10/29/2020 4:12:18 PM
hi_gene_to_
structure
_M Medium 17 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C
The collection of
structures
should serve as a valuable resource for biomedical research
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
14
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{5707B2E3-09B2-4FAE-824E-FD8FD64AF328}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2343
3023
This crystal structure shows a conserved hypothetical protein from <i>Mycobacterium tuberculosis</i>. Only 12 other proteins share its sequence homology, and none has a known function. This structure indicates the protein may play a role in metabolic pathways. Featured as one of the August 2007 Protein Structure Initiative Structures of the Month.
10/29/2020 2:48:36 PM
10/29/2020 2:48:36 PM
This
structure
indicates the protein may play a role in metabolic pathways
Featured as one of the August 2007 Protein
Structure
Initiative
Structures
of the Month
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
14
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{C049B741-42A1-4298-8E5F-15EE784B48B7}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2339
3083
NMR solution structure of a plant protein that may function in host defense. This protein was expressed in a convenient and efficient wheat germ cell-free system. Featured as the June 2007 Protein Structure Initiative Structure of the Month.
10/29/2020 2:40:04 PM
10/29/2020 2:40:04 PM
Type Name Media Type File Size Modified
Featured as the June 2007 Protein
Structure
Initiative
Structure
of the Month
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
14
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{47234FEB-EE1D-4DF6-A666-446A5C2D9E37}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2340
3084
This is the first structure of a protein derived from the metagenomic sequences collected during the Sorcerer II Global Ocean Sampling project. The crystal structure shows a barrel protein with a ferredoxin-like fold and a long chain fatty acid in a deep cleft (shaded red). Featured as one of the August 2007 Protein Structure Initiative Structures of the Month.
10/29/2020 2:41:27 PM
10/29/2020 2:41:27 PM
Type Name Media Type File Size Modified
2340_jcsg20d6_S Low 79 KB 3/29/2019 1:45 PM Constantinides, Stephen (NIH/NIGMS) [C
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
10
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{306636AD-6984-4103-B367-87B1EB3474FA}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2373
3087
Crystal structure of oligoendopeptidase F, a protein slicing enzyme from <i>Bacillus stearothermophilus</i>, a bacterium that can cause food products to spoil. The crystal was formed using a microfluidic capillary, a device that enables scientists to independently control the parameters for protein crystal nucleation and growth. Featured as one of the July 2007 Protein Structure Initiative Structures of the Month.
10/29/2020 4:30:39 PM
10/29/2020 4:30:39 PM
Type Name Media Type File Size Modified
Technologies Center for Gene to 3D
Structure
/Midwest Center for Structural Genomics
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
11
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{0D97FDE5-F4E0-4172-A7C4-8FCFDBC60F26}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2748
3272
This ribbon drawing of a protein hand drawn and colored by researcher Jane Richardson in 1981 helped originate the ribbon representation of proteins that is now ubiquitous in molecular graphics. The drawing shows the 3-dimensional structure of the protein triose phosphate isomerase. The green arrows represent the barrel of eight beta strands in this structure and the brown spirals show the protein's eight alpha helices. A black and white version of this drawing originally illustrated a <a href=http://kinemage.biochem.duke.edu/teaching/anatax target="_blank">review article</a> in <i>Advances in Protein Chemistry</i>, volume 34, titled "Anatomy and Taxonomy of Protein Structures." The illustration was selected as Picture of The Day on the English Wikipedia for November 19, 2009. Other important and beautiful images of protein structures by Jane Richardson are available in her <a href=http://commons.wikimedia.org/wiki/User:Dcrjsr/gallery_of_protein_structure target="_blank">Wikimedia gallery</a>.
8/18/2020 7:55:11 PM
8/18/2020 7:55:11 PM
The drawing shows the 3-dimensional
structure
of the protein triose phosphate isomerase
barrel of eight beta strands in this
structure
and the brown spirals show the protein's
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
10
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{463859B2-279A-4E80-A85C-A2382E815BD5}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3314
3415
Opioid receptors on the surfaces of brain cells are involved in pleasure, pain, addiction, depression, psychosis, and other conditions. The receptors bind to both innate opioids and drugs ranging from hospital anesthetics to opium. Researchers at The Scripps Research Institute, supported by the NIGMS Protein Structure Initiative, determined the first three-dimensional structure of a human opioid receptor, a kappa-opioid receptor. In this illustration, the submicroscopic receptor structure is shown while bound to an agonist (or activator). The structure is superimposed on a poppy flower, the source of opium. From a Scripps Research Institute <a href=http://www.scripps.edu/news/press/20120321stevens.html target="_blank">news release</a>.
12/23/2020 4:46:54 PM
12/23/2020 4:46:54 PM
by the NIGMS Protein
Structure
Initiative, determined the first three-dimensional
structure
of a human opioid receptor, a
Human opioid receptor
structure
superimposed on poppy
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
11
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{4BBF8D4D-E333-41E5-9B54-06A7AA38E085}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2365
3152
A global "map of the protein structure universe." The Berkeley Structural Genomics Center has developed a method to visualize the vast universe of protein structures in which proteins of similar structure are located close together and those of different structures far away in the space. This map, constructed using about 500 of the most common protein folds, reveals a highly non-uniform distribution, and shows segregation between four elongated regions corresponding to four different protein classes (shown in four different colors). Such a representation reveals a high-level of organization of the protein structure universe.
10/29/2020 4:16:23 PM
10/29/2020 4:16:23 PM
a representation reveals a high-level of organization of the protein
structure
universe
Map of protein
structures
01
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
15
5
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{2388E2EB-3730-4F33-A049-087CFC2A4AFF}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3487
3633
A special "messy" region of a potassium ion channel is important in its function.
9/8/2020 10:55:58 PM
9/8/2020 10:55:58 PM
BK_Virtual_
structure
_M Medium 253 KB 9/8/2020 6:52 PM Harris, Donald (NIH/NIGMS
BK_Virtual_
structure
_thumbnail Thumbnail 2 KB 9/8/2020 6:52 PM Harris, Donald
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
13
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{801B3D99-3943-4B03-9CF6-04BD027510D7}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2345
3024
Structure of a magnesium transporter protein from an antibiotic-resistant bacterium (<i>Enterococcus faecalis</i>) found in the human gut. Featured as one of the June 2007 Protein Sructure Initiative Structures of the Month.
10/29/2020 2:58:36 PM
10/29/2020 2:58:36 PM
Type Name Media Type File Size Modified
2345_nysgrc0618071_thumbnail Thumbnail 83 KB 3/4/2019 3:32 PM Constantinides, Stephen
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
15
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{DE4E47B3-0D83-483C-AC65-F8FE6D24E0B1}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2351
3029
An NMR solution structure model of the transfer RNA splicing enzyme endonuclease in humans (subunit Sen15). This represents the first structure of a eukaryotic tRNA splicing endonuclease subunit.
10/29/2020 3:06:53 PM
10/29/2020 3:06:53 PM
Type Name Media Type File Size Modified
2351_hi_2gw6_S Low 93 KB 3/29/2019 11:48 AM Constantinides, Stephen (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
11
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{95C0D2AD-AB59-4100-83B0-78CA3F50C76E}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2367
3153
A global "map of the protein structure universe" indicating the positions of specific proteins. The preponderance of small, less-structured proteins near the origin, with the more highly structured, large proteins towards the ends of the axes, may suggest the evolution of protein structures.
10/29/2020 4:18:37 PM
10/29/2020 4:18:37 PM
Type Name Media Type File Size Modified
hi_map500examples_L Low 82 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
15
6
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{8B5616E0-C0D5-468B-ACDC-A2D314BF8A73}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2355
3215
Model of the enzyme Nicotinic acid phosphoribosyltransferase. This enzyme, from the archaebacterium, <i>Pyrococcus furiosus</i>, is expected to be structurally similar to a clinically important human protein called B-cell colony enhancing factor based on amino acid sequence similarities and structure prediction methods. The structure consists of identical protein subunits, each shown in a different color, arranged in a ring.
10/29/2020 3:44:23 PM
10/29/2020 3:44:23 PM
factor based on amino acid sequence similarities and
structure
prediction methods
The
structure
consists of identical protein subunits, each shown in a different color
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
20
9
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{32F0F10A-7087-466D-BEE4-36238144FEC6}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2338
3082
Model of a member from the Tex protein family, which is implicated in transcriptional regulation and highly conserved in eukaryotes and prokaryotes. The structure shows significant homology to a human transcription elongation factor that may regulate multiple steps in mRNA synthesis.
10/29/2020 2:37:40 PM
10/29/2020 2:37:40 PM
Type Name Media Type File Size Modified
burleyd Thumbnail 7 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C
Molecular
Structures
protein
structure
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
14
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{35294316-7B85-4707-83F4-B824CBA718BB}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3584
3580
This image shows a computer-generated, three-dimensional map of the rotavirus structure. This virus infects humans and other animals and causes severe diarrhea in infants and young children. By the age of five, almost every child in the world has been infected with this virus at least once. Scientists have found a vaccine against rotavirus, so in the United States there are very few fatalities, but in developing countries and in places where the vaccine is unavailable, this virus is responsible for more than 450,000 deaths each year.<Br><Br> The rotavirus comprises three layers: the outer, middle and inner layers. On infection, the outer layer is removed, leaving behind a "double-layered particle." Researchers have studied the structure of this double-layered particle with a transmission electron microscope. Many images of the virus at a magnification of ~50,000x were acquired, and computational analysis was used to combine the individual particle images into a three-dimensional reconstruction. <Br><Br>The image was rendered by Melody Campbell (PhD student at TSRI). Work that led to the 3D map was published in Campbell et al. Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure. 2012;20(11):1823-8. PMCID: PMC3510009. <Br><Br>This image was part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.
11/22/2022 8:55:40 PM
11/22/2022 8:55:40 PM
Researchers have studied the
structure
of this double-layered particle with a transmission
This image shows a computer-generated, three-dimensional map of the rotavirus
structure
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
9
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{38997347-01E8-4B63-97E7-3CD152CD4331}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2352
3030
Model of aspartoacylase, a human enzyme involved in brain metabolism.
10/29/2020 3:08:25 PM
10/29/2020 3:08:25 PM
Type Name Media Type File Size Modified
2352_hi_2i3c_S Low 113 KB 3/29/2019 11:47 AM Constantinides, Stephen (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
11
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{816D0D7B-ED59-4000-BF2A-0FCB0B539282}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2381
3031
Model of an enzyme, dUTP pyrophosphatase, from <i>Mycobacterium tuberculosis</i>. Drugs targeted to this enzyme might inhibit the replication of the bacterium that causes most cases of tuberculosis.
10/29/2020 4:45:35 PM
10/29/2020 4:45:35 PM
Type Name Media Type File Size Modified
2381_hi_Rv2697c_S Low 120 KB 3/29/2019 11:31 AM Constantinides, Stephen (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
9
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{BA90BC5B-5136-4E5A-A949-B4104A70F686}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2392
3222
A crystal of sheep hemoglobin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.
10/29/2020 4:58:13 PM
10/29/2020 4:58:13 PM
Type Name Media Type File Size Modified
f02A_sheep_hemoglobin_S Low 50 KB 9/7/2016 3:07 PM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
12
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{1FAC4EF0-38F5-4FC0-9A20-47A56101DC30}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2374
3088
A knotted protein from an archaebacterium called <i>Methanobacterium thermoautotrophicam</i>. This organism breaks down waste products and produces methane gas. Protein folding theory previously held that forming a knot was beyond the ability of a protein, but this structure, determined at Argonne's Structural Biology Center, proves differently. Researchers theorize that this knot stabilizes the amino acid subunits of the protein.
10/29/2020 4:32:27 PM
10/29/2020 4:32:27 PM
Type Name Media Type File Size Modified
hi_Pg08_knotCover_M Medium 124 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
14
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{0E71151F-877D-4350-81C9-DA68215951CA}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3477
3698
This image is a computer-generated model of the approximately 4.2 million atoms of the HIV capsid, the shell that contains the virus' genetic material. Scientists determined the exact structure of the capsid and the proteins that it's made of using a variety of imaging techniques and analyses. They then entered these data into a supercomputer that produced the atomic-level image of the capsid. This structural information could be used for developing drugs that target the capsid, possibly leading to more effective therapies
11/14/2023 1:23:33 PM
11/14/2023 1:23:33 PM
Type Name Media Type File Size Modified
Scientists determined the exact
structure
of the capsid and the proteins that it's made of using a
3D
structure
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
18
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{4475C347-ACA7-4D71-B1A5-B70167940ACF}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3421
3428
Some children are born with a mutation in a regulatory site on this enzyme that causes them to over-secrete insulin when they consume protein. We found that a compound from green tea (shown in the stick figure and by the yellow spheres on the enzyme) is able to block this hyperactivity when given to animals with this disorder.
8/12/2020 5:55:18 AM
8/12/2020 5:55:18 AM
Type Name Media Type File Size Modified
Smith_Green_Tea High 2787 KB 6/3/2016 3:28 PM aamishral2 (NIH/NIGMS) [C
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
19
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{E483CD08-3B80-435E-AA0D-C99D7F88A233}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3413
3493
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Found in the journal, Nature, Chemical Biology 8, 366-374 (2012). Series of seven images. Related to <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3414">image 3414</a> , <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3415">image 3415</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3416">image 3416</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3417">image 3417</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3418">image 3418</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3419">image 3419</a>.
12/23/2020 11:02:46 PM
12/23/2020 11:02:46 PM
Type Name Media Type File Size Modified
X-ray co-crystal
structure
of Src kinase bound to a DNA-templated macrocycle inhibitor 1
WE are happy to give you
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
11
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{082D0675-FCFD-4E1E-9ECB-FE9441E456BA}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3418
3498
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Found in the journal, Nature, Chemical Biology 8, 366-374 (2012). <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3413">image 3413</a> , <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3414">image 3414</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3415">image 3415</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3416">image 3416</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3417">image 3417</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3419">image 3419</a>.
12/23/2020 11:12:00 PM
12/23/2020 11:12:00 PM
Type Name Media Type File Size Modified
X-ray co-crystal
structure
of Src kinase bound to a DNA-templated macrocycle inhibitor 6
WE are happy to give you
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
13
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{151298FF-60F5-42C1-8AA6-94F7FD3186DD}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2413
3098
A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.
8/6/2020 7:45:47 PM
8/6/2020 7:45:47 PM
Type Name Media Type File Size Modified
f07S_pig_trypsin1_S Low 32 KB 9/7/2016 3:42 PM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
12
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{62D6C832-61B1-433F-9F03-CBC6AD58F57F}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2402
3158
A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.
8/6/2020 6:44:52 PM
8/6/2020 6:44:52 PM
Type Name Media Type File Size Modified
f06D_RNase_A1_S Low 65 KB 9/7/2016 3:26 PM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
8
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{84664409-B084-46D1-9095-ED7222988EF4}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2400
3228
A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.
8/6/2020 4:08:55 PM
8/6/2020 4:08:55 PM
Type Name Media Type File Size Modified
f02O_porcine_trypsin1_S Low 39 KB 9/7/2016 3:23 PM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
8
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{5646CC83-D78E-46EF-BDEC-2BD0C94CB76E}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3748
3600
Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. The proteins that span this membrane play an important role in the life cycle of the virus. Scientists used cryo-EM to determine the structure of a dengue virus at a 3.5-angstrom resolution to reveal how the membrane proteins undergo major structural changes as the virus matures and infects a host. For more on cryo-EM see the blog post <a href="https://biobeat.nigms.nih.gov/2016/02/cryo-electron-microscopy-reveals-molecules-in-ever-greater-detail/">Cryo-Electron Microscopy Reveals Molecules in Ever Greater Detail</a>. For a still image of the dengue virus surface structure, see <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3756">image 3756.<a>
12/17/2020 5:44:50 PM
12/17/2020 5:44:50 PM
Scientists used cryo-EM to determine the
structure
of a dengue virus at a 3.5-angstrom resolution to
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
8
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{C1CE1840-548F-4D9E-B330-AE1522A52391}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
6902
3826
An <em> Arachnoidiscus</em> diatom with a diameter of 190µm. Diatoms are microscopic algae that have cell walls made of silica, which is the strongest known biological material relative to its density. In <em> Arachnoidiscus</em>, the cell wall is a radially symmetric pillbox-like shell composed of overlapping halves that contain intricate and delicate patterns. Sometimes, <em> Arachnoidiscus</em> is called “a wheel of glass.” <Br><Br> This image was taken with the orientation-independent differential interference contrast microscope.
7/13/2022 8:00:33 PM
7/13/2022 8:00:33 PM
Fourth of July_S Low 40 KB
A red Ferris wheel-like
structure
with a blue background
red and blue round
structure
that looks like a ferris wheel, fireworks, Independence Day
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
12
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{061D17CD-3B20-4996-B7BC-CC797BDA0A6D}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3358
3296
The receptor is shown bound to a partial inverse agonist, carazolol
12/23/2020 5:41:41 PM
12/23/2020 5:41:41 PM
Type Name Media Type File Size Modified
b2AR_1300x1500_S Low 75 KB 9/14/2016 11:35 AM Varkala, Venkat (NIH/NIGMS) [C
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
7
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{FD6EE021-80A5-420F-963E-D5B9F45D5BCB}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2411
3096
Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.
8/6/2020 7:42:01 PM
8/6/2020 7:42:01 PM
Type Name Media Type File Size Modified
f07N_fungal_lipase1_S Low 30 KB 9/7/2016 3:39 PM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
13
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{00CC22CD-D661-4A46-B76C-2BF83B279865}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3493
3567
Like a watch wrapped around a wrist, a special enzyme encircles the double helix to repair a broken strand of DNA. Without molecules that can mend such breaks, cells can malfunction, die, or become cancerous. Related to image <a href="https://imagesadminprod.nigms.nih.gov/Pages/DetailPage.aspx?imageID=131">2330</a>.
9/9/2020 2:16:07 AM
9/9/2020 2:16:07 AM
Type Name Media Type File Size Modified
GDB--DNA_unwinding_recolored Other 11273 KB 9/26/2020 10:40 PM Harris, Donald (NIH
structure
, proteins
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
13
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{F2218257-80D3-4C95-A593-3F1D0092301B}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2346
3025
Model of a human protein associated with the adenylyl cyclase, an enzyme involved in intracellular signaling.
10/29/2020 3:00:19 PM
10/29/2020 3:00:19 PM
Type Name Media Type File Size Modified
2346_th_1k8f_S Low 53 KB 3/29/2019 11:50 AM Constantinides, Stephen (NIH/NIGMS) [C
protein
structure
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
15
6
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{B6534242-F2E6-4D37-8A57-C9F8F5724860}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2596
3387
In the top snapshots, the brain of a sleep-deprived fruit fly glows orange, marking high concentrations of a synaptic protein called Bruchpilot (BRP) involved in communication between neurons. The color particularly lights up brain areas associated with learning. By contrast, the bottom images from a well-rested fly show lower levels of the protein. These pictures illustrate the results of an April 2009 study showing that sleep reduces the protein's levels, suggesting that such "downscaling" resets the brain to normal levels of synaptic activity and makes it ready to learn after a restful night. Featured in the May 20, 2009, issue of <a href=http://publications.nigms.nih.gov/biobeat/09-05-20/index.html#1 target="_blank"><em>Biomedical Beat</em></a>.
10/30/2020 7:21:43 PM
10/30/2020 7:21:43 PM
Type Name Media Type File Size Modified
sleep_fly1_L Low 9 KB 6/3/2016 3:13 PM aamishral2 (NIH/NIGMS) [C
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
7
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{179D8D15-FAF6-4541-9811-87052DBCC0B8}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3616
3650
The lubber grasshopper, found throughout the southern United States, is frequently used in biology classes to teach students about the respiratory system of insects. Unlike mammals, which have red blood cells that carry oxygen throughout the body, insects have breathing tubes that carry air through their exoskeleton directly to where it's needed. This image shows the breathing tubes embedded in the weblike sheath cells that cover developing egg chambers. This image is part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.
11/28/2022 9:47:06 PM
11/28/2022 9:47:06 PM
Type Name Media Type File Size Modified
10_3_grasshopper-ovary-Edwards-3000px Other 39595 KB 10/25/2020 9:44 PM Harris, Donald
Structure
, insect
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
7
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{E134B4F1-837B-44F9-84B7-BA084A3E76DF}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3617
3651
This image shows a normal fibroblast, a type of cell that is common in connective tissue and frequently studied in research labs. This cell has a healthy skeleton composed of actin (red) and microtubles (green). Actin fibers act like muscles to create tension and microtubules act like bones to withstand compression. This image is part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.
11/22/2022 9:18:45 PM
11/22/2022 9:18:45 PM
Type Name Media Type File Size Modified
5_right_Cell_keep_their_shape_with_actin_and_microtubules_L Low 150 KB 6/3/2016 3:34 PM
Structure
, system
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
7
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{D856BBEC-A16B-4798-982B-454A9289AC04}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2337
3081
Crystal structure of the beta2-adrenergic receptor protein. This is the first known structure of a human G protein-coupled receptor, a large family of proteins that control critical bodily functions and the action of about half of today's pharmaceuticals. Featured as one of the November 2007 Protein Structure Initiative Structures of the Month.
10/29/2020 2:35:50 PM
10/29/2020 2:35:50 PM
Type Name Media Type File Size Modified
2337_beta2-adrenergic_T Thumbnail 108 KB 3/29/2019 1:47 PM Constantinides, Stephen
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
13
2
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{55028E4D-1BE0-45A9-BB7C-A6F9AA03316D}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
1272
3129
The three fibers of the cytoskeleton--microtubules in blue, intermediate filaments in red, and actin in green--play countless roles in the cell. Appears in the NIGMS booklet <a href="http://publications.nigms.nih.gov/insidethecell/" target="_blank"><i>Inside the Cell</i></a>.
10/28/2020 4:14:44 PM
10/28/2020 4:14:44 PM
Type Name Media Type File Size Modified
ITC_Cytoskeleton_S Low 144 KB 8/24/2016 3:18 PM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
15
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{E37185A4-4561-456C-AC76-3A1F352FA533}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2799
3278
Force vectors computed from actin cytoskeleton flow. This is an example of NIH-supported research on single cell analysis. Related to <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2798">image 2798</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2800">image 2800</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2801">image 2801</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2802">image 2802</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2803">image 2803</a>.
9/11/2020 4:23:33 PM
9/11/2020 4:23:33 PM
Type Name Media Type File Size Modified
nih11IntracellularForces_S Low 92 KB 8/24/2016 3:41 PM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
7
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{3D55FE55-96A4-40D3-8C11-D9AADE15FC17}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2802
3281
A rendering of an activity biosensor image overlaid with a cell-centered frame of reference used for image analysis of signal transduction. This is an example of NIH-supported research on single cell analysis. Related to <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2798">image 2798</a> , <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2799">image 2799</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2800">image 2800</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2801">image 2801</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2803">image 2803</a>.
9/11/2020 4:25:46 PM
9/11/2020 4:25:46 PM
Type Name Media Type File Size Modified
nih11BiosensorsArtistic_L Low 133 KB 6/3/2016 3:18 PM aamishral2 (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
8
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{74662892-4E9F-4C75-A089-54EB98B3D0BA}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
5883
3557
Composite image of beta-galactosidase showing how cryo-EM’s resolution has improved dramatically in recent years. Older images to the left, more recent to the right. Related to image <a href="https://images.nigms.nih.gov/Pages/DetailPage.aspx?imageID2=5882">5882</a>. NIH Director Francis Collins featured this on his blog on January 14, 2016. See<a href="https://directorsblog.nih.gov/2016/01/14/got-it-down-cold-cryo-electron-microscopy-named-method-of-the-year/"> Got It Down Cold: Cryo-Electron Microscopy Named Method of the Year </a>
12/18/2020 9:52:10 PM
12/18/2020 9:52:10 PM
Type Name Media Type File Size Modified
BlueGold_BetaGalactosidase_beige_M Medium 92 KB 5/11/2017 11:46 AM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
8
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{6E2F4831-F581-426A-832A-1DACE83D0D6A}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
3755
3605
The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). On the left, the HIV capsid is "naked," a state in which it would be easily detected by and removed from cells. However, as shown on the right, when the viral capsid binds to and is covered with a host protein, called cyclophilin A (shown in red), it evades detection and enters and invades the human cell to use it to establish an infection. To learn more about how cyclophilin A helps HIV infect cells and how scientists used cryo-EM to find out the mechanism by which the HIV capsid attaches to cyclophilin A, <a href="https://news.illinois.edu/blog/view/6367/335013">see this news release by the University of Illinois</a>. A study reporting these findings was published in the journal <a href="http://www.nature.com/ncomms/2016/160304/ncomms10714/full/ncomms10714.html"><i>Nature Communications</i></a>.
12/17/2020 6:19:59 PM
12/17/2020 6:19:59 PM
Type Name Media Type File Size Modified
HIV capsid square crop Thumbnail 152 KB 10/13/2016 12:57 PM Machalek, Alisa (NIH/NIAMS) [E
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
8
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{0E29D964-8A3C-4D5E-8F31-BC20B251F865}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
6901
3825
A 20-µm thick section of mouse midbrain. The nerve cells are transparent and weren’t stained. Instead, the color is generated by interaction of white polarized light with the molecules in the cells and indicates their orientation. <Br><Br>The image was obtained with a polychromatic polarizing microscope that shows the polychromatic birefringent image with hue corresponding to the slow axis orientation. More information about the microscopy that produced this image can be found in the <em>Scientific Reports</em> paper <a href="https://www.nature.com/articles/srep17340/">“Polychromatic Polarization Microscope: Bringing Colors to a Colorless World”</a> by Shribak.
6/30/2022 12:16:01 PM
6/30/2022 12:16:01 PM
Type Name Media Type File Size Modified
Brain Slice_S Low 10 KB 7/13/2022 4:07 PM Bigler, Abbey (NIH/NIGMS) [C
More information about the microscopy that produced this image can be found in
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
11
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{ED8899BF-3F30-4957-A9CB-6F1530901C7A}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
6848
3851
A model of the molecule himastatin, which was first isolated from the bacterium <em>Streptomyces himastatinicus</em>. Himastatin shows antibiotic activity. The researchers who created this image developed a new, more concise way to synthesize himastatin so it can be studied more easily. <Br><Br> More information about the research that produced this image can be found in the <em>Science</em> paper <a href="https://www.science.org/doi/10.1126/science.abm6509">“Total synthesis of himastatin”</a> by D’Angelo et al. <Br><Br> Related to image <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6850">6850</a> and video <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6851">6851</a>.
3/7/2022 9:09:53 PM
3/7/2022 9:09:53 PM
Type Name Media Type File Size Modified
Movassaghi-HimastatinMol_S Low 13 KB 3/7/2022 4:05 PM Bigler, Abbey (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
12
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{38E54214-2D53-42A7-995E-F98376409CB4}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
6851
3853
A 360-degree view of the molecule himastatin, which was first isolated from the bacterium <em>Streptomyces himastatinicus</em>. Himastatin shows antibiotic activity. The researchers who created this video developed a new, more concise way to synthesize himastatin so it can be studied more easily. <Br><Br> More information about the research that produced this video can be found in the <em>Science</em> paper <a href="https://www.science.org/doi/10.1126/science.abm6509">“Total synthesis of himastatin”</a> by D’Angelo et al. <Br><Br> Related to images <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6848">6848</a> and <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6850">6850</a>.
3/7/2022 9:12:07 PM
3/7/2022 9:12:07 PM
Type Name Media Type File Size Modified
HimastatinStill Thumbnail 473 KB 3/4/2022 2:57 PM Bigler, Abbey (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
15
8
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{CF79B1B6-6BF8-4B4A-A7FE-871AB2AB50A9}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2417
3100
This fruit fly expresses green fluorescent protein (GFP) in the same pattern as the period gene, a gene that regulates circadian rhythm and is expressed in all sensory neurons on the surface of the fly.
8/6/2020 7:51:34 PM
8/6/2020 7:51:34 PM
Type Name Media Type File Size Modified
FlybyNight1_S Low 11 KB 9/7/2016 5:33 PM Varkala, Venkat (NIH/NIGMS) [C
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
19
4
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{03C5A6E6-05E4-4B1A-884E-53940CDDCD3D}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
6601
3836
This animation shows atoms of the HIV capsid, the shell that encloses the virus's genetic material. Scientists determined the exact structure of the capsid using a variety of imaging techniques and analyses. They then entered this data into a supercomputer to produce this image. Related to image <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=3477">3477</a>.
11/14/2023 1:23:27 PM
11/14/2023 1:23:27 PM
Atomic-Level
Structure
of the HIV Capsid High 20229 KB 12/10/2020 5:41 PM
atomic-level
structure
of HIV capsid_thumbnail Thumbnail 12 KB 12/10/2020
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
21
5
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{2C77B30F-B214-4301-B475-E0433A651C12}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2372
3157
Crystal structure of a protein with unknown function from <i>Xanthomonas campestris</i>, a plant pathogen. Eight copies of the protein crystallized to form a ring. Chosen as the December 2007 Protein Structure Initiative Structure of the Month.
10/29/2020 4:26:44 PM
10/29/2020 4:26:44 PM
Type Name Media Type File Size Modified
Chosen as the December 2007 Protein
Structure
Initiative
Structure
of the Month
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
10
3
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{87B885D1-27EB-4EB7-8EEB-FFD75998D185}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31
2354
3214
Electron density maps such as this one are generated from the diffraction patterns of X-rays passing through protein crystals. These maps are then used to generate a model of the protein's structure by fitting the protein's amino acid sequence (yellow) into the observed electron density (blue).
10/29/2020 3:42:22 PM
10/29/2020 3:42:22 PM
Type Name Media Type File Size Modified
hi_3a_isas_map_L Low 49 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C
Molecular
Structures
STS_ListItem_DocumentLibrary
https://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx
12
5
0
https://images.nigms.nih.gov
html
True
https://imagesadmin.nigms.nih.gov
{7219C040-55C6-48C5-A3B0-A1A1A03C2919}
Sharepoint.DocumentSet
~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js
31
31