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34383370The chemical structure of the morphine molecule8/22/2020 4:44:39 PM8/22/2020 4:44:39 PMMorphine_structure__thumbnail_    Thumbnail 2 KB 6/3/2016 3:29 PM aamishral2 (NIH Morphine_structure_L    High 4772 KB 6/3/2016 3:29 PM aamishral2 (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1340https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{6EE205B7-C53B-4A56-B1E5-DB767CF5273F}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23423086X-ray structure of a new DNA repair enzyme superfamily representative from the human gastrointestinal bacterium <i>Enterococcus faecalis</i>. European scientists used this structure to generate homologous structures. Featured as the May 2007 Protein Structure Initiative Structure of the Month.10/29/2020 2:46:36 PM10/29/2020 2:46:36 PMEuropean scientists used this structure to generate homologous structures Featured as the May 2007 Protein Structure Initiative Structure of the Month STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1440https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{985DEF74-B19F-428E-A73F-96B3A80C5557}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23633150The goal of the PSI is to determine the three-dimensional shapes of a wide range of proteins by solving the structures of representative members of each protein family found in nature. The collection of structures should serve as a valuable resource for biomedical research scientists.10/29/2020 4:12:18 PM10/29/2020 4:12:18 PMhi_gene_to_structure_M    Medium 17 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C The collection of structures should serve as a valuable resource for biomedical research STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1440https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{5707B2E3-09B2-4FAE-824E-FD8FD64AF328}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23433023This crystal structure shows a conserved hypothetical protein from <i>Mycobacterium tuberculosis</i>. Only 12 other proteins share its sequence homology, and none has a known function. This structure indicates the protein may play a role in metabolic pathways. Featured as one of the August 2007 Protein Structure Initiative Structures of the Month.10/29/2020 2:48:36 PM10/29/2020 2:48:36 PMThis structure indicates the protein may play a role in metabolic pathways Featured as one of the August 2007 Protein Structure Initiative Structures of the Month STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1440https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{C049B741-42A1-4298-8E5F-15EE784B48B7}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23393083NMR solution structure of a plant protein that may function in host defense. This protein was expressed in a convenient and efficient wheat germ cell-free system. Featured as the June 2007 Protein Structure Initiative Structure of the Month.10/29/2020 2:40:04 PM10/29/2020 2:40:04 PMType    Name    Media Type    File Size    Modified Featured as the June 2007 Protein Structure Initiative Structure of the Month Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1440https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{47234FEB-EE1D-4DF6-A666-446A5C2D9E37}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23403084This is the first structure of a protein derived from the metagenomic sequences collected during the Sorcerer II Global Ocean Sampling project. The crystal structure shows a barrel protein with a ferredoxin-like fold and a long chain fatty acid in a deep cleft (shaded red). Featured as one of the August 2007 Protein Structure Initiative Structures of the Month.10/29/2020 2:41:27 PM10/29/2020 2:41:27 PMType    Name    Media Type    File Size    Modified 2340_jcsg20d6_S    Low 79 KB 3/29/2019 1:45 PM Constantinides, Stephen (NIH/NIGMS) [C Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1030https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{306636AD-6984-4103-B367-87B1EB3474FA}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23733087Crystal structure of oligoendopeptidase F, a protein slicing enzyme from <i>Bacillus stearothermophilus</i>, a bacterium that can cause food products to spoil. The crystal was formed using a microfluidic capillary, a device that enables scientists to independently control the parameters for protein crystal nucleation and growth. Featured as one of the July 2007 Protein Structure Initiative Structures of the Month.10/29/2020 4:30:39 PM10/29/2020 4:30:39 PMType    Name    Media Type    File Size    Modified Technologies Center for Gene to 3D Structure/Midwest Center for Structural Genomics Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1140https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{0D97FDE5-F4E0-4172-A7C4-8FCFDBC60F26}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
27483272This ribbon drawing of a protein hand drawn and colored by researcher Jane Richardson in 1981 helped originate the ribbon representation of proteins that is now ubiquitous in molecular graphics. The drawing shows the 3-dimensional structure of the protein triose phosphate isomerase. The green arrows represent the barrel of eight beta strands in this structure and the brown spirals show the protein's eight alpha helices. A black and white version of this drawing originally illustrated a <a href=http://kinemage.biochem.duke.edu/teaching/anatax target="_blank">review article</a> in <i>Advances in Protein Chemistry</i>, volume 34, titled "Anatomy and Taxonomy of Protein Structures." The illustration was selected as Picture of The Day on the English Wikipedia for November 19, 2009. Other important and beautiful images of protein structures by Jane Richardson are available in her <a href=http://commons.wikimedia.org/wiki/User:Dcrjsr/gallery_of_protein_structure target="_blank">Wikimedia gallery</a>.8/18/2020 7:55:11 PM8/18/2020 7:55:11 PMThe drawing shows the 3-dimensional structure of the protein triose phosphate isomerase barrel of eight beta strands in this structure and the brown spirals show the protein's STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1030https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{463859B2-279A-4E80-A85C-A2382E815BD5}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
33143415Opioid receptors on the surfaces of brain cells are involved in pleasure, pain, addiction, depression, psychosis, and other conditions. The receptors bind to both innate opioids and drugs ranging from hospital anesthetics to opium. Researchers at The Scripps Research Institute, supported by the NIGMS Protein Structure Initiative, determined the first three-dimensional structure of a human opioid receptor, a kappa-opioid receptor. In this illustration, the submicroscopic receptor structure is shown while bound to an agonist (or activator). The structure is superimposed on a poppy flower, the source of opium. From a Scripps Research Institute <a href=http://www.scripps.edu/news/press/20120321stevens.html target="_blank">news release</a>.12/23/2020 4:46:54 PM12/23/2020 4:46:54 PMby the NIGMS Protein Structure Initiative, determined the first three-dimensional structure of a human opioid receptor, a Human opioid receptor structure superimposed on poppy STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1140https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{4BBF8D4D-E333-41E5-9B54-06A7AA38E085}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23653152A global "map of the protein structure universe." The Berkeley Structural Genomics Center has developed a method to visualize the vast universe of protein structures in which proteins of similar structure are located close together and those of different structures far away in the space. This map, constructed using about 500 of the most common protein folds, reveals a highly non-uniform distribution, and shows segregation between four elongated regions corresponding to four different protein classes (shown in four different colors). Such a representation reveals a high-level of organization of the protein structure universe.10/29/2020 4:16:23 PM10/29/2020 4:16:23 PMa representation reveals a high-level of organization of the protein structure universe Map of protein structures 01 Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1550https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{2388E2EB-3730-4F33-A049-087CFC2A4AFF}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
34873633A special "messy" region of a potassium ion channel is important in its function.9/8/2020 10:55:58 PM9/8/2020 10:55:58 PMBK_Virtual_structure_M    Medium 253 KB 9/8/2020 6:52 PM Harris, Donald (NIH/NIGMS BK_Virtual_structure_thumbnail    Thumbnail 2 KB 9/8/2020 6:52 PM Harris, Donald STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1340https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{801B3D99-3943-4B03-9CF6-04BD027510D7}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23453024Structure of a magnesium transporter protein from an antibiotic-resistant bacterium (<i>Enterococcus faecalis</i>) found in the human gut. Featured as one of the June 2007 Protein Sructure Initiative Structures of the Month.10/29/2020 2:58:36 PM10/29/2020 2:58:36 PMType    Name    Media Type    File Size    Modified 2345_nysgrc0618071_thumbnail    Thumbnail 83 KB 3/4/2019 3:32 PM Constantinides, Stephen Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1540https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{DE4E47B3-0D83-483C-AC65-F8FE6D24E0B1}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23513029An NMR solution structure model of the transfer RNA splicing enzyme endonuclease in humans (subunit Sen15). This represents the first structure of a eukaryotic tRNA splicing endonuclease subunit.10/29/2020 3:06:53 PM10/29/2020 3:06:53 PMType    Name    Media Type    File Size    Modified 2351_hi_2gw6_S    Low 93 KB 3/29/2019 11:48 AM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1130https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{95C0D2AD-AB59-4100-83B0-78CA3F50C76E}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23673153A global "map of the protein structure universe" indicating the positions of specific proteins. The preponderance of small, less-structured proteins near the origin, with the more highly structured, large proteins towards the ends of the axes, may suggest the evolution of protein structures.10/29/2020 4:18:37 PM10/29/2020 4:18:37 PMType    Name    Media Type    File Size    Modified hi_map500examples_L    Low 82 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1560https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{8B5616E0-C0D5-468B-ACDC-A2D314BF8A73}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23553215Model of the enzyme Nicotinic acid phosphoribosyltransferase. This enzyme, from the archaebacterium, <i>Pyrococcus furiosus</i>, is expected to be structurally similar to a clinically important human protein called B-cell colony enhancing factor based on amino acid sequence similarities and structure prediction methods. The structure consists of identical protein subunits, each shown in a different color, arranged in a ring.10/29/2020 3:44:23 PM10/29/2020 3:44:23 PMfactor based on amino acid sequence similarities and structure prediction methods The structure consists of identical protein subunits, each shown in a different color STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx2090https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{32F0F10A-7087-466D-BEE4-36238144FEC6}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23383082Model of a member from the Tex protein family, which is implicated in transcriptional regulation and highly conserved in eukaryotes and prokaryotes. The structure shows significant homology to a human transcription elongation factor that may regulate multiple steps in mRNA synthesis.10/29/2020 2:37:40 PM10/29/2020 2:37:40 PMType    Name    Media Type    File Size    Modified burleyd    Thumbnail 7 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C Molecular Structures protein structure STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1430https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{35294316-7B85-4707-83F4-B824CBA718BB}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
35843580This image shows a computer-generated, three-dimensional map of the rotavirus structure. This virus infects humans and other animals and causes severe diarrhea in infants and young children. By the age of five, almost every child in the world has been infected with this virus at least once. Scientists have found a vaccine against rotavirus, so in the United States there are very few fatalities, but in developing countries and in places where the vaccine is unavailable, this virus is responsible for more than 450,000 deaths each year.<Br><Br> The rotavirus comprises three layers: the outer, middle and inner layers. On infection, the outer layer is removed, leaving behind a "double-layered particle." Researchers have studied the structure of this double-layered particle with a transmission electron microscope. Many images of the virus at a magnification of ~50,000x were acquired, and computational analysis was used to combine the individual particle images into a three-dimensional reconstruction. <Br><Br>The image was rendered by Melody Campbell (PhD student at TSRI). Work that led to the 3D map was published in Campbell et al. Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure. 2012;20(11):1823-8. PMCID: PMC3510009. <Br><Br>This image was part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.11/22/2022 8:55:40 PM11/22/2022 8:55:40 PMResearchers have studied the structure of this double-layered particle with a transmission This image shows a computer-generated, three-dimensional map of the rotavirus structure STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx930https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{38997347-01E8-4B63-97E7-3CD152CD4331}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23523030Model of aspartoacylase, a human enzyme involved in brain metabolism.10/29/2020 3:08:25 PM10/29/2020 3:08:25 PMType    Name    Media Type    File Size    Modified 2352_hi_2i3c_S    Low 113 KB 3/29/2019 11:47 AM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1130https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{816D0D7B-ED59-4000-BF2A-0FCB0B539282}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23813031Model of an enzyme, dUTP pyrophosphatase, from <i>Mycobacterium tuberculosis</i>. Drugs targeted to this enzyme might inhibit the replication of the bacterium that causes most cases of tuberculosis.10/29/2020 4:45:35 PM10/29/2020 4:45:35 PMType    Name    Media Type    File Size    Modified 2381_hi_Rv2697c_S    Low 120 KB 3/29/2019 11:31 AM Constantinides, Stephen (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx930https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{BA90BC5B-5136-4E5A-A949-B4104A70F686}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23923222A crystal of sheep hemoglobin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.10/29/2020 4:58:13 PM10/29/2020 4:58:13 PMType    Name    Media Type    File Size    Modified f02A_sheep_hemoglobin_S    Low 50 KB 9/7/2016 3:07 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1230https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{1FAC4EF0-38F5-4FC0-9A20-47A56101DC30}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23743088A knotted protein from an archaebacterium called <i>Methanobacterium thermoautotrophicam</i>. This organism breaks down waste products and produces methane gas. Protein folding theory previously held that forming a knot was beyond the ability of a protein, but this structure, determined at Argonne's Structural Biology Center, proves differently. Researchers theorize that this knot stabilizes the amino acid subunits of the protein.10/29/2020 4:32:27 PM10/29/2020 4:32:27 PMType    Name    Media Type    File Size    Modified hi_Pg08_knotCover_M    Medium 124 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1430https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{0E71151F-877D-4350-81C9-DA68215951CA}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
34773698This image is a computer-generated model of the approximately 4.2 million atoms of the HIV capsid, the shell that contains the virus' genetic material. Scientists determined the exact structure of the capsid and the proteins that it's made of using a variety of imaging techniques and analyses. They then entered these data into a supercomputer that produced the atomic-level image of the capsid. This structural information could be used for developing drugs that target the capsid, possibly leading to more effective therapies11/14/2023 1:23:33 PM11/14/2023 1:23:33 PMType    Name    Media Type    File Size    Modified Scientists determined the exact structure of the capsid and the proteins that it's made of using a 3D structure STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1840https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{4475C347-ACA7-4D71-B1A5-B70167940ACF}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
34213428Some children are born with a mutation in a regulatory site on this enzyme that causes them to over-secrete insulin when they consume protein. We found that a compound from green tea (shown in the stick figure and by the yellow spheres on the enzyme) is able to block this hyperactivity when given to animals with this disorder.8/12/2020 5:55:18 AM8/12/2020 5:55:18 AMType    Name    Media Type    File Size    Modified Smith_Green_Tea    High 2787 KB 6/3/2016 3:28 PM aamishral2 (NIH/NIGMS) [C Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1930https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{E483CD08-3B80-435E-AA0D-C99D7F88A233}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
34133493X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Found in the journal, Nature, Chemical Biology 8, 366-374 (2012). Series of seven images. Related to <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3414">image 3414</a> , <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3415">image 3415</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3416">image 3416</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3417">image 3417</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3418">image 3418</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3419">image 3419</a>.12/23/2020 11:02:46 PM12/23/2020 11:02:46 PMType    Name    Media Type    File Size    Modified X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1 WE are happy to give you STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1130https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{082D0675-FCFD-4E1E-9ECB-FE9441E456BA}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
34183498X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Found in the journal, Nature, Chemical Biology 8, 366-374 (2012). <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3413">image 3413</a> , <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3414">image 3414</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3415">image 3415</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3416">image 3416</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3417">image 3417</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3419">image 3419</a>.12/23/2020 11:12:00 PM12/23/2020 11:12:00 PMType    Name    Media Type    File Size    Modified X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 6 WE are happy to give you STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1330https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{151298FF-60F5-42C1-8AA6-94F7FD3186DD}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
24133098A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.8/6/2020 7:45:47 PM8/6/2020 7:45:47 PMType    Name    Media Type    File Size    Modified f07S_pig_trypsin1_S    Low 32 KB 9/7/2016 3:42 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1230https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{62D6C832-61B1-433F-9F03-CBC6AD58F57F}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
24023158A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.8/6/2020 6:44:52 PM8/6/2020 6:44:52 PMType    Name    Media Type    File Size    Modified f06D_RNase_A1_S    Low 65 KB 9/7/2016 3:26 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx830https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{84664409-B084-46D1-9095-ED7222988EF4}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
24003228A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.8/6/2020 4:08:55 PM8/6/2020 4:08:55 PMType    Name    Media Type    File Size    Modified f02O_porcine_trypsin1_S    Low 39 KB 9/7/2016 3:23 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx830https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{5646CC83-D78E-46EF-BDEC-2BD0C94CB76E}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
37483600Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. The proteins that span this membrane play an important role in the life cycle of the virus. Scientists used cryo-EM to determine the structure of a dengue virus at a 3.5-angstrom resolution to reveal how the membrane proteins undergo major structural changes as the virus matures and infects a host. For more on cryo-EM see the blog post <a href="https://biobeat.nigms.nih.gov/2016/02/cryo-electron-microscopy-reveals-molecules-in-ever-greater-detail/">Cryo-Electron Microscopy Reveals Molecules in Ever Greater Detail</a>. For a still image of the dengue virus surface structure, see <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=3756">image 3756.<a>12/17/2020 5:44:50 PM12/17/2020 5:44:50 PMScientists used cryo-EM to determine the structure of a dengue virus at a 3.5-angstrom resolution to STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx830https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{C1CE1840-548F-4D9E-B330-AE1522A52391}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
69023826An <em> Arachnoidiscus</em> diatom with a diameter of 190µm. Diatoms are microscopic algae that have cell walls made of silica, which is the strongest known biological material relative to its density. In <em> Arachnoidiscus</em>, the cell wall is a radially symmetric pillbox-like shell composed of overlapping halves that contain intricate and delicate patterns. Sometimes, <em> Arachnoidiscus</em> is called “a wheel of glass.” <Br><Br> This image was taken with the orientation-independent differential interference contrast microscope. 7/13/2022 8:00:33 PM7/13/2022 8:00:33 PMFourth of July_S    Low 40 KB A red Ferris wheel-like structure with a blue background red and blue round structure that looks like a ferris wheel, fireworks, Independence Day STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1240https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{061D17CD-3B20-4996-B7BC-CC797BDA0A6D}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
33583296The receptor is shown bound to a partial inverse agonist, carazolol12/23/2020 5:41:41 PM12/23/2020 5:41:41 PMType    Name    Media Type    File Size    Modified b2AR_1300x1500_S    Low 75 KB 9/14/2016 11:35 AM Varkala, Venkat (NIH/NIGMS) [C Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx730https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{FD6EE021-80A5-420F-963E-D5B9F45D5BCB}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
24113096Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures.8/6/2020 7:42:01 PM8/6/2020 7:42:01 PMType    Name    Media Type    File Size    Modified f07N_fungal_lipase1_S    Low 30 KB 9/7/2016 3:39 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1340https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{00CC22CD-D661-4A46-B76C-2BF83B279865}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
34933567Like a watch wrapped around a wrist, a special enzyme encircles the double helix to repair a broken strand of DNA. Without molecules that can mend such breaks, cells can malfunction, die, or become cancerous. Related to image <a href="https://imagesadminprod.nigms.nih.gov/Pages/DetailPage.aspx?imageID=131">2330</a>. 9/9/2020 2:16:07 AM9/9/2020 2:16:07 AMType    Name    Media Type    File Size    Modified GDB--DNA_unwinding_recolored    Other 11273 KB 9/26/2020 10:40 PM Harris, Donald (NIH structure, proteins STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1340https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{F2218257-80D3-4C95-A593-3F1D0092301B}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23463025Model of a human protein associated with the adenylyl cyclase, an enzyme involved in intracellular signaling.10/29/2020 3:00:19 PM10/29/2020 3:00:19 PMType    Name    Media Type    File Size    Modified 2346_th_1k8f_S    Low 53 KB 3/29/2019 11:50 AM Constantinides, Stephen (NIH/NIGMS) [C protein structure STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1560https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{B6534242-F2E6-4D37-8A57-C9F8F5724860}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
25963387In the top snapshots, the brain of a sleep-deprived fruit fly glows orange, marking high concentrations of a synaptic protein called Bruchpilot (BRP) involved in communication between neurons. The color particularly lights up brain areas associated with learning. By contrast, the bottom images from a well-rested fly show lower levels of the protein. These pictures illustrate the results of an April 2009 study showing that sleep reduces the protein's levels, suggesting that such "downscaling" resets the brain to normal levels of synaptic activity and makes it ready to learn after a restful night. Featured in the May 20, 2009, issue of <a href=http://publications.nigms.nih.gov/biobeat/09-05-20/index.html#1 target="_blank"><em>Biomedical Beat</em></a>.10/30/2020 7:21:43 PM10/30/2020 7:21:43 PMType    Name    Media Type    File Size    Modified sleep_fly1_L    Low 9 KB 6/3/2016 3:13 PM aamishral2 (NIH/NIGMS) [C Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx730https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{179D8D15-FAF6-4541-9811-87052DBCC0B8}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
36163650The lubber grasshopper, found throughout the southern United States, is frequently used in biology classes to teach students about the respiratory system of insects. Unlike mammals, which have red blood cells that carry oxygen throughout the body, insects have breathing tubes that carry air through their exoskeleton directly to where it's needed. This image shows the breathing tubes embedded in the weblike sheath cells that cover developing egg chambers. This image is part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.11/28/2022 9:47:06 PM11/28/2022 9:47:06 PMType    Name    Media Type    File Size    Modified 10_3_grasshopper-ovary-Edwards-3000px    Other 39595 KB 10/25/2020 9:44 PM Harris, Donald Structure, insect STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx730https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{E134B4F1-837B-44F9-84B7-BA084A3E76DF}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
36173651This image shows a normal fibroblast, a type of cell that is common in connective tissue and frequently studied in research labs. This cell has a healthy skeleton composed of actin (red) and microtubles (green). Actin fibers act like muscles to create tension and microtubules act like bones to withstand compression. This image is part of the Life: Magnified collection, which was displayed in the Gateway Gallery at Washington Dulles International Airport June 3, 2014, to January 21, 2015. To see all 46 images in this exhibit, go to https://www.nigms.nih.gov/education/life-magnified/Pages/default.aspx.11/22/2022 9:18:45 PM11/22/2022 9:18:45 PMType    Name    Media Type    File Size    Modified 5_right_Cell_keep_their_shape_with_actin_and_microtubules_L    Low 150 KB 6/3/2016 3:34 PM Structure, system STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx730https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{D856BBEC-A16B-4798-982B-454A9289AC04}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23373081Crystal structure of the beta2-adrenergic receptor protein. This is the first known structure of a human G protein-coupled receptor, a large family of proteins that control critical bodily functions and the action of about half of today's pharmaceuticals. Featured as one of the November 2007 Protein Structure Initiative Structures of the Month.10/29/2020 2:35:50 PM10/29/2020 2:35:50 PMType    Name    Media Type    File Size    Modified 2337_beta2-adrenergic_T    Thumbnail 108 KB 3/29/2019 1:47 PM Constantinides, Stephen Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1320https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{55028E4D-1BE0-45A9-BB7C-A6F9AA03316D}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
12723129The three fibers of the cytoskeleton--microtubules in blue, intermediate filaments in red, and actin in green--play countless roles in the cell. Appears in the NIGMS booklet <a href="http://publications.nigms.nih.gov/insidethecell/" target="_blank"><i>Inside the Cell</i></a>.10/28/2020 4:14:44 PM10/28/2020 4:14:44 PMType    Name    Media Type    File Size    Modified ITC_Cytoskeleton_S    Low 144 KB 8/24/2016 3:18 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1540https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{E37185A4-4561-456C-AC76-3A1F352FA533}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
27993278Force vectors computed from actin cytoskeleton flow. This is an example of NIH-supported research on single cell analysis. Related to <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2798">image 2798</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2800">image 2800</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2801">image 2801</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2802">image 2802</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2803">image 2803</a>.9/11/2020 4:23:33 PM9/11/2020 4:23:33 PMType    Name    Media Type    File Size    Modified nih11IntracellularForces_S    Low 92 KB 8/24/2016 3:41 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx730https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{3D55FE55-96A4-40D3-8C11-D9AADE15FC17}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
28023281A rendering of an activity biosensor image overlaid with a cell-centered frame of reference used for image analysis of signal transduction. This is an example of NIH-supported research on single cell analysis. Related to <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2798">image 2798</a> , <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2799">image 2799</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2800">image 2800</a>, <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2801">image 2801</a> and <a href="https://imagesadminprod.nigms.nih.gov/index.cfm?event=viewDetail&imageID=2803">image 2803</a>.9/11/2020 4:25:46 PM9/11/2020 4:25:46 PMType    Name    Media Type    File Size    Modified nih11BiosensorsArtistic_L    Low 133 KB 6/3/2016 3:18 PM aamishral2 (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx830https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{74662892-4E9F-4C75-A089-54EB98B3D0BA}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
58833557Composite image of beta-galactosidase showing how cryo-EM’s resolution has improved dramatically in recent years. Older images to the left, more recent to the right. Related to image <a href="https://images.nigms.nih.gov/Pages/DetailPage.aspx?imageID2=5882">5882</a>. NIH Director Francis Collins featured this on his blog on January 14, 2016. See<a href="https://directorsblog.nih.gov/2016/01/14/got-it-down-cold-cryo-electron-microscopy-named-method-of-the-year/"> Got It Down Cold: Cryo-Electron Microscopy Named Method of the Year </a>12/18/2020 9:52:10 PM12/18/2020 9:52:10 PMType    Name    Media Type    File Size    Modified BlueGold_BetaGalactosidase_beige_M    Medium 92 KB 5/11/2017 11:46 AM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx830https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{6E2F4831-F581-426A-832A-1DACE83D0D6A}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
37553605The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). On the left, the HIV capsid is "naked," a state in which it would be easily detected by and removed from cells. However, as shown on the right, when the viral capsid binds to and is covered with a host protein, called cyclophilin A (shown in red), it evades detection and enters and invades the human cell to use it to establish an infection. To learn more about how cyclophilin A helps HIV infect cells and how scientists used cryo-EM to find out the mechanism by which the HIV capsid attaches to cyclophilin A, <a href="https://news.illinois.edu/blog/view/6367/335013">see this news release by the University of Illinois</a>. A study reporting these findings was published in the journal <a href="http://www.nature.com/ncomms/2016/160304/ncomms10714/full/ncomms10714.html"><i>Nature Communications</i></a>.12/17/2020 6:19:59 PM12/17/2020 6:19:59 PMType    Name    Media Type    File Size    Modified HIV capsid square crop    Thumbnail 152 KB 10/13/2016 12:57 PM Machalek, Alisa (NIH/NIAMS) [E STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx840https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{0E29D964-8A3C-4D5E-8F31-BC20B251F865}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
69013825A 20-µm thick section of mouse midbrain. The nerve cells are transparent and weren’t stained. Instead, the color is generated by interaction of white polarized light with the molecules in the cells and indicates their orientation. <Br><Br>The image was obtained with a polychromatic polarizing microscope that shows the polychromatic birefringent image with hue corresponding to the slow axis orientation. More information about the microscopy that produced this image can be found in the <em>Scientific Reports</em> paper <a href="https://www.nature.com/articles/srep17340/">“Polychromatic Polarization Microscope: Bringing Colors to a Colorless World”</a> by Shribak. 6/30/2022 12:16:01 PM6/30/2022 12:16:01 PMType    Name    Media Type    File Size    Modified Brain Slice_S    Low 10 KB 7/13/2022 4:07 PM Bigler, Abbey (NIH/NIGMS) [C More information about the microscopy that produced this image can be found in STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1140https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{ED8899BF-3F30-4957-A9CB-6F1530901C7A}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
68483851A model of the molecule himastatin, which was first isolated from the bacterium <em>Streptomyces himastatinicus</em>. Himastatin shows antibiotic activity. The researchers who created this image developed a new, more concise way to synthesize himastatin so it can be studied more easily. <Br><Br> More information about the research that produced this image can be found in the <em>Science</em> paper <a href="https://www.science.org/doi/10.1126/science.abm6509">“Total synthesis of himastatin”</a> by D’Angelo et al. <Br><Br> Related to image <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6850">6850</a> and video <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6851">6851</a>.3/7/2022 9:09:53 PM3/7/2022 9:09:53 PMType    Name    Media Type    File Size    Modified Movassaghi-HimastatinMol_S    Low 13 KB 3/7/2022 4:05 PM Bigler, Abbey (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1240https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{38E54214-2D53-42A7-995E-F98376409CB4}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
68513853A 360-degree view of the molecule himastatin, which was first isolated from the bacterium <em>Streptomyces himastatinicus</em>. Himastatin shows antibiotic activity. The researchers who created this video developed a new, more concise way to synthesize himastatin so it can be studied more easily. <Br><Br> More information about the research that produced this video can be found in the <em>Science</em> paper <a href="https://www.science.org/doi/10.1126/science.abm6509">“Total synthesis of himastatin”</a> by D’Angelo et al. <Br><Br> Related to images <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6848">6848</a> and <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=6850">6850</a>.3/7/2022 9:12:07 PM3/7/2022 9:12:07 PMType    Name    Media Type    File Size    Modified HimastatinStill    Thumbnail 473 KB 3/4/2022 2:57 PM Bigler, Abbey (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1580https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{CF79B1B6-6BF8-4B4A-A7FE-871AB2AB50A9}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
24173100This fruit fly expresses green fluorescent protein (GFP) in the same pattern as the period gene, a gene that regulates circadian rhythm and is expressed in all sensory neurons on the surface of the fly.8/6/2020 7:51:34 PM8/6/2020 7:51:34 PMType    Name    Media Type    File Size    Modified FlybyNight1_S    Low 11 KB 9/7/2016 5:33 PM Varkala, Venkat (NIH/NIGMS) [C STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1940https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{03C5A6E6-05E4-4B1A-884E-53940CDDCD3D}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
66013836This animation shows atoms of the HIV capsid, the shell that encloses the virus's genetic material. Scientists determined the exact structure of the capsid using a variety of imaging techniques and analyses. They then entered this data into a supercomputer to produce this image. Related to image <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=3477">3477</a>. 11/14/2023 1:23:27 PM11/14/2023 1:23:27 PMAtomic-Level Structure of the HIV Capsid    High 20229 KB 12/10/2020 5:41 PM atomic-level structure of HIV capsid_thumbnail    Thumbnail 12 KB 12/10/2020 STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx2150https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{2C77B30F-B214-4301-B475-E0433A651C12}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23723157Crystal structure of a protein with unknown function from <i>Xanthomonas campestris</i>, a plant pathogen. Eight copies of the protein crystallized to form a ring. Chosen as the December 2007 Protein Structure Initiative Structure of the Month.10/29/2020 4:26:44 PM10/29/2020 4:26:44 PMType    Name    Media Type    File Size    Modified Chosen as the December 2007 Protein Structure Initiative Structure of the Month Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1030https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{87B885D1-27EB-4EB7-8EEB-FFD75998D185}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131
23543214Electron density maps such as this one are generated from the diffraction patterns of X-rays passing through protein crystals. These maps are then used to generate a model of the protein's structure by fitting the protein's amino acid sequence (yellow) into the observed electron density (blue).10/29/2020 3:42:22 PM10/29/2020 3:42:22 PMType    Name    Media Type    File Size    Modified hi_3a_isas_map_L    Low 49 KB 6/3/2016 3:09 PM aamishral2 (NIH/NIGMS) [C Molecular Structures STS_ListItem_DocumentLibraryhttps://images.nigms.nih.gov/PublicAssets/Forms/AllItems.aspx1250https://images.nigms.nih.govhtmlTruehttps://imagesadmin.nigms.nih.gov{7219C040-55C6-48C5-A3B0-A1A1A03C2919}Sharepoint.DocumentSet~sitecollection/_catalogs/masterpage/Display Templates/Search/Item_PublicAsset.js3131