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  • 300731525882480150315752676647750785833341PublicAssets/3730The image visualizes a part of the yeast molecular interaction network. The lines in the network represent connections among genes (shown as little dots) and different-colored networks indicate subnetworks, for instance, those in specific locations or pathways in the cell. Researchers use gene or protein expression data to build these networks; the network shown here was visualized with a program called <a href="http://cytoscape.org/">Cytoscape</a>. By following changes in the architectures of these networks in response to altered environmental conditions, scientists can home in on those genes that become central "hubs" (highly connected genes), for example, when a cell encounters stress. They can then further investigate the precise role of these genes to uncover how a cell's molecular machinery deals with stress or other factors. Related to images <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=3732">3732</a> and <a href="https://images.nigms.nih.gov/pages/DetailPage.aspx?imageid2=3733">3733</a>.Keiichiro Ono, UCSDKeiichiro Ono and Trey Ideker, UCSDIllustration

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    GenesTools and Techniques

    A molecular interaction network in yeast 1

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    The image visualizes a part of the yeast molecular interaction network. The lines in the network represent connections among genes (shown as little dots) and different-colored networks indicate subnetworks, for instance, those in specific locations or pathways in the cell. Researchers use gene or protein expression data to build these networks; the network shown here was visualized with a program called Cytoscape. By following changes in the architectures of these networks in response to altered environmental conditions, scientists can home in on those genes that become central "hubs" (highly connected genes), for example, when a cell encounters stress. They can then further investigate the precise role of these genes to uncover how a cell's molecular machinery deals with stress or other factors. Related to images 3732 and 3733.

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    Keiichiro Ono, UCSD

    Credit Line

    Keiichiro Ono and Trey Ideker, UCSD

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    Illustration

    ID

    3730

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