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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. The illustration includes a cartoon with four frames and a fifth frame with potential applications. For an explanation and overview of the CRISPR-Cas9 system, see the NIGMS Biomedical Beat blog entry at Field Focus: Precision Gene Editing with CRISPR and the iBiology video at http://www.ibiology.org/ibiomagazine/jennifer-doudna-genome-engineering-with-crispr-cas9-birth-of-a-breakthrough-technology.html.
National Institute of General Medical Sciences, National Institutes of Health
Illustration
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