Detail Page

  • 2000267125554001000133520411447964170796PublicAssets/3444Taste buds in a circumvallate papilla in a mouse tongue with types I, II and III taste cells visualized by cell-type-specific fluorescent antibodies. Type II cells respond to sweet, bitter, and umami tastes by signaling to the central nervous system by non-vesicular ATP release. Taruno and colleagues have identified CALHM1 as a voltage-gated ATP release channel that mediates this response to these taste modalities. The work was published in Nature (14 March 2013) and supported in part by the National Institutes of Health (GM56328, MH059937, NS072775, DC10393, EY13624, R03DC011143, P30 EY001583, P30DC011735). A news release about the work can be read <a href=http://www.uphs.upenn.edu/news/news_releases/2013/03/foskett/ target="blank"> <em>here.</em></a>Aki Taruno, Perelman School of Medicine, University of Pennsylvania; NaturePhotograph

    Topic Tags:

    Cells

    Taste Buds

    View EntryAdd to My Images

    Taste buds in a circumvallate papilla in a mouse tongue with types I, II and III taste cells visualized by cell-type-specific fluorescent antibodies. Type II cells respond to sweet, bitter, and umami tastes by signaling to the central nervous system by non-vesicular ATP release. Taruno and colleagues have identified CALHM1 as a voltage-gated ATP release channel that mediates this response to these taste modalities. The work was published in Nature (14 March 2013) and supported in part by the National Institutes of Health (GM56328, MH059937, NS072775, DC10393, EY13624, R03DC011143, P30 EY001583, P30DC011735). A news release about the work can be read here.

    Source

    Credit Line

    Aki Taruno, Perelman School of Medicine, University of Pennsylvania; Nature

    Record Type

    Photograph

    ID

    3444

My Images/Videos