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  • 35057698062175288932030828465379PublicAssets/3426Normal mice, like the B6 breed pictured on the left, develop scars when their ears are pierced. The Murphy Roths Large (MRL) mice pictured on the right can grow back lost ear tissue thanks to an inactive version of the p21 gene. When researchers knocked out that same gene in other mouse breeds, their ears also healed completely without scarring. Journal Article: Clark, L.D., Clark, R.K. and Heber-Katz, E. 1998. A new murine model for mammalian wound repair and regeneration. Clin Immunol Immunopathol 88: 35-45.Ellen Heber-Katz, The Wistar InstituteDoug Thayer, University of Pennsylvania School of Veterinary Medicine and Ellen Heber-Katz, The Wistar InstitutePhotograph

    Regeneration of Mouse Ears

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    Normal mice, like the B6 breed pictured on the left, develop scars when their ears are pierced. The Murphy Roths Large (MRL) mice pictured on the right can grow back lost ear tissue thanks to an inactive version of the p21 gene. When researchers knocked out that same gene in other mouse breeds, their ears also healed completely without scarring. Journal Article: Clark, L.D., Clark, R.K. and Heber-Katz, E. 1998. A new murine model for mammalian wound repair and regeneration. Clin Immunol Immunopathol 88: 35-45.

    Source

    Ellen Heber-Katz, The Wistar Institute

    Credit Line

    Doug Thayer, University of Pennsylvania School of Veterinary Medicine and Ellen Heber-Katz, The Wistar Institute

    Record Type

    Photograph

    ID

    3426

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